"They start folks off on 10mg twice again and may increase it slowly to see if hair regrows. If you are in the group that regrows hair to be cosmetically acceptable, then they will slowly taper the dosage to 5 mg twice a day. The worry is risking…"
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Dupilumab For Alopecia
Started May 15, 2019 0 Replies 0 Likes
There is some researcher buzz about allergy medicines and a drug called dupilumab being effective in AA (an immunomodulatory med). Anyone know of current studies? Continue
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"It is in clinical trials for hair loss with about a 50% success rate, but the FDA has not cleared it as of yet due to potential side effects which can be very serious. Glad it works for you on both fronts! "
"Apparently, that is not such a rare occurrence according to the team of researchers at Columbia Presbyterian. They told her no more vaccines and now her college, St. Olaf is threatening to kick her out due to not being able to get the covid vaccine.…"
"Sounds like a real jerk! But, keep the faith that most folks are supportive and alopecia can strike anyone at anytime. After a routine booster, my then 18 year old daughter lost all her hair three years ago and never recovered. It has taken some…"
"My daughter lost all her hair at 18 after her MenACWY booster right before leaving for college. While she does have some sporadic regrowth, she has lost 95% of all her hair including eyebrows and lashes. She is doing great in school and enjoys a…"
"Hey Magmck,
Think the most current research (as of August 2019) does show that after 10 years the follicle response rate is much lower; however, all this is evolving and lots of new treatments are being investigated with the biologics. Have you…"
"While I have not taken xeljanz, I have been up to Yale and to Columbia Pres. to meet with some of the experts on this dosage. It can take 8-10 months to see regrowth on a JAK2 inhibitor. Start with 5 mg twice daily and increased to 10mg if needed…"
"My daughter's journey began with AA at 18 right before departing for college. While she has chosen to be very open about it because living in a dorm created hardship and stress with concealing her AU. It has been a growing experience and now…"
"Columbia/Pres was looking at FMT (fecal microbiota transplant) as a possible treatment. It is currently used for antibiotic resistant C diff infections. Apparently, two AU patients who developed antibiotic resistant C diff infections in the hospital…"
"Aclaris scrapped their topical JAK 2 for ineffectiveness. I thought it had pretty much been abandoned by many due to the lack of good regrowth. Pfizer may be coming out with a JAK2 oral for alopecia. Very true that there are lots of biologics in the…"
"What was your dose of Dupixient? Did you participate in the trial in NYC at Rockefeller U? "
"If this trial is successful, it will be offered throughout the U.S. You cannot get the 600 mg does outside the trial currently even if you want it. Will update the group as more info is available.
Gut microbial issues might be the villain in…"
"Gut Dysbiosis In Alopecia Areata Patients Reveals Overabundance of Firmicutes
and Under Representation of Bacteroides
Brigitte N. Sallee MD1, Rolando Perez-Lorenzo PhD1, Eddy HC. Wang PhD1, Alexa R. Abdelaziz1, James C. Chen PhD1, Lindsey A. Bordone…"
"Think there is a new 10 year safety study out about JAK 2 inhibitors. The last material I saw showed a 3% lifetime risk of getting lymphoma while using this class of meds. It looks like most of cases were older and had multiple auto immune…"
"Maybe another med would work for you, dupilumab. I am not sure what the progress is at this point, but some alopecians have fully regrown their hair and rolled off the meds. Believe the trial is for 600 mg injectable per…"
Dupilumab For Alopecia
There is some researcher buzz about allergy medicines and a drug called dupilumab being effective in AA (an immunomodulatory med). Anyone know of current studies? See More
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