CTP-543 trial--anyone start it yet?

I've been watching the trial for the drug by Concert Pharma called CTP-543.  It hasn't started in my area but according to the governmt website they are started in a few places:  https://clinicaltrials.gov/ct2/show/NCT03137381?term=ctp-543&ra...  Rancho Mirage, New Haven (CT), Portland, Houston and a couple other places.  Anyone lucky enough to get on the study yet?  It's a newer version of Rux.

Views: 3724

▶ Reply to This

Replies to This Discussion

Permalink Reply by AM on October 14, 2019 at 7:54pm

How are the side effects?

Permalink Reply by AM on October 14, 2019 at 7:55pm

I am contimplating the PZier trial.. not sure what the difference is?

Permalink Reply by serg navaro on October 14, 2019 at 10:33pm

I’m in week 9 and have yet to have any side effects. Hair is definitely growing 

Permalink Reply by Chi_Loss on October 15, 2019 at 12:59pm

i am in week 10 and no side effects. inital vellus hair has turned darker and more vellus popping up...very excited.

Permalink Reply by serg navaro on October 15, 2019 at 1:19pm

That’s exciting!! Mine started off as thin vellus hairs but are starting to get thicker and fill in, especially around my temples. Glad you’re also having success so far :)

Permalink Reply by Chi_Loss on December 31, 2019 at 12:57pm

i have about 60% regrowth (from totalis) with more vellus coming in on the stubborn parts. i have ophiasis pattern hair loss so sides and back are difficult for me. I am excited to say that the dosage study ends in January and i am moving to the extension study which should go until the drug gets to market. I think I could have optimal regrowth in another 4 or 5 months. it took a bit for it to start but now is coming in pretty steady... no side effects so far.

Permalink Reply by serg navaro on January 2, 2020 at 12:11pm

Wow thats awesome! I am at about 80-85% regrowth from almost 100% loss on my scalp. I am finishing up my 24 weeks in 4 weeks then going on to the extension study.I definitely have some stubborn spots still.

Permalink Reply by AM on January 2, 2020 at 12:43pm

How long did it take for you to see a sign of life lol?  I started the pfizer clinical trial about a month ago and I believe I am on 50mg.  I haven't stopped shedding yet (albeit maybe slowed down a bit) but I'm slowly heading towards unversalis (am totalis already).  I know i need to be patient but just thought I'd see how long it took to start to see some growth (I've heard once it starts - its onwards and upwards from there)... thanks!

Permalink Reply by serg navaro on January 2, 2020 at 2:40pm

I started seeing growth after about 2 months, started off very thin and fine and now its all starting to thicken and fill in. Lots of patience is a must. 

Permalink Reply by Chi_Loss on January 2, 2020 at 3:48pm

It took me about 10 weeks to see vellus (that felt like FOREVER) then it slowly darkened and lengthened. Its like watching a pot of water boil...but it does seem to come in steadily once it darkens up. I also had continued shedding when i started, it was scary but i know from experience that sometime the disease continues on its course before it stops then starts to actually grow. Hang in there! heard great things about the pfizer results...

Permalink Reply by serg navaro on January 3, 2020 at 10:09am

It really does feel like forever! Glad your e also having results, I`m excited to continue onto the extension study

Permalink Reply by serg navaro on January 28, 2020 at 9:23am
I was just rolled over onto the extension study and my doctor told me that I will be on the medication up until it hits the market! Very exciting, however my doctor lowered my prescription to 8 mg pills instead of keeping me on 12mg. Apparently everyone on 12mg have elevated potassium levels. So he wants to see if my potassium level lowers on 8 mg and will put me back up to 12mg if it does lower.

I have rolled over onto the extension study and was told that I will be on the medication until the drug hits the market, very exciting! However my doctor dropped my dosage to 8mg pills twice daily instead of 12mg, apparently all subjects are having elevated potassium levels on 12mg so he wants to see if it`ll lower on 8mg. If it does then he will re evaluate and put me back on 12mg. Have you had any potassium elevations?

RSS

Disclaimer

Any mention of products and services on Alopecia World is for informational purposes only; it does not imply a recommendation or endorsement by Alopecia World. Nor should any statement or representation on this site be construed as professional, medical or expert advice, or as pre-screened or endorsed by Alopecia World. Alopecia World is not responsible or liable for any of the views, opinions or conduct, online or offline, of any user or member of Alopecia World.

© 2024   Created by Alopecia World.   Powered by

Badges  |  Report an Issue  |  Terms of Service