Hiya,

Quick background - I am 25 and started experiencing aggressive alopecia around 3 years ago. I was not happy with the diagnosis a dermatologist gave me and got a scalp biopsy to only confirm which of what I thought was a farce. 

My dermatologist is dated with the information he knows and will refuse to prescribe anything of use to me. I've lost a great deal of hair around my nape and above the ears and I am extremely anxious to even step outside. I don't look good without hair, I need it for my own dwindling mental health to stay a float.

First off, I went really hard at possible hormonal causes of hairloss by fully chemically castrating myself; I've been a eunuch for the best part of five years. Next I used the usual, Dutasteride and topical RU8841. At his point I thought my hairloss was caused because of being a male means you have a hormonal reason for your hair to fall out. (DHT and elevated DHEAS). After several bloodtests I was able to bring down my endogenous s-x hormone production to near 0 for both LH and FSH. Even my serum testosterone was never > or = to 50ngl/dl. Eventually I surgically removed those parts because i am terrified of losing my hair.

Now for when I got the scalp biopsy, the diagnosis was keratosis pilaris; and if you look online there is near blooming nothing that says how to treat it other than if you had it KP on a place like your arms. Essentially KP is an overproduction of keratin in the skin which can cause the hair follicles to plug up and then get forcibly ejected from the scalp. My dermatologist has been milking my wallet for all the money I have for the past hair ignoring my concerns and only prescribing me emollients and other things hat have been placebo in effect.  

I have large patches of skin where hair does not grow on the sides of my head, betamethasone and lymecycline has not done anything; and my freaking derm won't prescribe anything else. Seeing another derm would mean being a new patient with the cost of registering as a new patient which would only cost more money that I don't' have to run in a circle like a chicken with a stick up its bum. 

Im stressed. I tried pioglitazone since that apparently has some autoimmune/anti-inflammatory stuff going on at an increased risk of bladder cancer. But still no dice, even if I wanted to try something like tofacitinib or baracitinib; its always in bulk only from India and usually many more boxes than what constitutes as a 3 month supply that customs allows. Plus looking at the costs, its too rich for my peasant blood.

I cannot stress how important my hair is, you can like or hate what I have already said or about to say. I used to be a transgender. If I don't have hair, then I just look like a monster. 

list of meda that haven't worked;

minoxidil

dutasteride

cyproterone acetate

lueprorelide

pioglitazone

betamethasone

lymecycline

RU58841

I've lost.