These two articles cover most of the bases on our questions:

Genetic basis of alopecia areata -- one of most common causes of ...
www.sciencedaily.com/releases/2010/06/100630132744.htm
Jun 30, 2010 – ScienceDaily: Your source for the latest research news and science ... "Finding the initial genes underlying alopecia areata is a big step forward ...

Alopecia Areata
emedicine.medscape.com/article/1069931-overview
Apr 3, 2012 – Alopecia areata is a recurrent nonscarring type of hair loss that can ... News; Reference; Education; MEDLINE .... Finally, the high association of Down syndrome with alopecia areata suggests involvement of a gene located on ...

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