Hi everyone,

I wanted to share about the advancing biotechnology CRISPR, which is a gene editing tool that can precisely edit out the gene that causes diseases. It gets to the root of the problem which is in our dna, the gene expression of this disease making the hair follicle lose immune privilege and allowing it to be attacked. Editing this gene out and replacing it with the gene with immune privilege, our hair will remain intact. Solving this issue is basically curing the disease verses what we currently have which are bandaid solution drugs that are all immune altering / suppression drugs that can lead to risks of other serious diseases such as cancer, infection, etc. This technology recently got a lot more attn in the news because they had their first successful case with sickle cell. They are working on HIV, cancers and other diseases as well. If you’re excited about jak inhibitors (which i see as a short term solution because of the risks i mentioned above), CRISPR is what we should be paying close attn to and asking our doctors, NAAF to advocate for scientists to develop a solution for Alopecia and eczema and related dermatological conditions that are usually grouped together. CRISPR is new-ish gaining traction in the last few years but I think this really is promising for all of us. 

Happy holidays!

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And it's gonna cost more than a million dollars. Most of us won't be able to get it 

when is this envisioned, it really wont help if its 20 years from now

Technology is rapidly advancing, so it might not be as far as we think. But we have to do our part and keep this conversation going with doctors and the NAAF to keep this as a goal to find a cure instead of immune suppressing drugs that has detrimental side effects and currently unknown long term effects of the jak inhibitors. 

As well in regards to cost, treatments should be made accessible to people. We need NAAF and our legislative representatives to advocate for affordable treatments for all that need it.  Ayanna Pressley has been very visible recently as someone with influence that also understands our plight. We should all be reaching out and making it known that our health matters and AA, AT, AU deserves the attention in genome technology advancement for finding a cure. And be persistent and refuse to accept “no” for an answer. 

I've had patchy alopecia areata since 2015. Still have my eyebrows and body hair, but on my head there's a few large patches. For a while now I've been contemplating getting all the hair on my head removed by laser, for that clean, smooth bald head slick look. Another huge benefit would be that I wouldn't have to spend close to 30 minutes every day shaving my head as close as I possibly can. However, I'm scared that I'll laser it all off, only for some cure to be released shortly after I've done it, and then all the hair follicles will be completely dead as opposed to the current state of dormancy they're in. Big dilemma for me personally, and I was leaning towards just doing it and accepting that I'll never have hair again. My reasoning was that while jak1/2 might've worked for me, the potential side effects greatly outweighs the upside. If I'm understanding you correct, this could potentially just "turn off" the immune response towards hair, while not causing the side effects seen from the immunosupressives? Do you have more sources or info you could share on this subject? 

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