the ATI-50001 and ATI-50002 thread

ATI-50001 is another selective JAK inhibitor being developed by Aclaris Therapeutics. 


Aclaris is developing and testing an oral and topical version called ATI-50002. The oral version is currently in phase 1 testing (12 patient test) and the topical is in pre-clinical testing (I believe this means they have "healthy" people using it to see if there are any adverse affects

relevant links

http://www.aclaristx.com/pipeline

https://globenewswire.com/news-release/2016/10/31/884660/0/en/Aclar...

Please use this thread for any information you come across about ATI-50001 or ATI-50002 to help those of us obsessing over future treatment options :)

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Replies to This Discussion

Permalink Reply by chris_s on May 3, 2018 at 9:30pm

Glad you’re doing well!

are you in the topical or oral trial?

Permalink Reply by Zach on May 3, 2018 at 10:10pm

Topical

Permalink Reply by Hope4mySON on May 4, 2018 at 10:27am

how long did u have alopecia for

Permalink Reply by Zach on May 4, 2018 at 1:52pm

I’ve had Alopecia for 20 years. 

Permalink Reply by Hope4mySON on May 4, 2018 at 3:17pm

did  u have patchy? what type did u have

Permalink Reply by Zach on May 4, 2018 at 4:19pm

Yes. Patchy. I’ve shaved my head since I was 19. I wrote about my experiences in childhood Here .

Permalink Reply by chris_s on July 2, 2018 at 10:03pm

Hey Zach, 

looking forward to reading your 3 month update :)

Permalink Reply by Kim_t on September 17, 2018 at 12:17am

I just started phase 2 of the topical trial. When you used the topical did you have any tingling or effects from the medication?  Im only in week 1 of using it, but hopeful the tingling means I got the medicine and not the placebo. 

Permalink Reply by Zach on July 3, 2018 at 11:21pm
3 Month update -

Negative Side Effects:
No negative side effects.
Positive Side Effects:
Increased growth. Growth is very slow, but I'm still encouraged. Most of my head is covered with the peach fuzzy translucent white hairs. This is fuzzier than my head has been in over a decade. Usually when I would grow it out in the past ten years,there would always be significant bald spots. Right now, there is not.Because of that fact, I lean towards thinking I don't have a placebo.
Permalink Reply by kimk on July 4, 2018 at 1:47pm

Nice .... are you on topical or pill. When will study end and you lose the med?

Permalink Reply by Zach on July 4, 2018 at 3:02pm

Topical. Three months left in the study. 

Permalink Reply by chris_s on July 4, 2018 at 6:21pm

Thank you for the comprehensive update! 

 Please post again at the end of your trial or earlier if anything interesting happens 

Good luck!

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