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Alopecia universalis treatment
Hi everyone! I am a new member here. Are here people who tried treatment with NAC and methyl forms of vitamins B?
I have alopecia since 2010 when I was 19. It became universalis in 2012. I never tried immunosuppressant therapy, however I know it could help if I try. But I believe that it could make things worse after treatment cancellation.
I am trying not to inhibit my immunity, but make it work on right way.
I tried different things, and last one was NAC + melatonin + selenium. It worked since last June until November. My hair grew back about 85% on head and I also has some brows and eyelashes.
But when it became cold, it stopped working. I dod not know the reason and I started to Google again :)
I found that NAC does not work without active forms of folic acid and b12. And if you have MTHFR mutation, then you cannot produce active forms. I read before that the reason of illness might be oxidative stress that caused by free radicals. And I did tests on genes of folate cycle and detoxification system. They found mutations in following genes: MTHFR, MTRR, GSTT1, NAT2 (5b*).
That means I have problems with methyl forms if vitamins and detoxification. I started to take active forms if these vitamins and increased the dosage of NAC. Now I am waiting for results.
Is there anybody who did such tests or who is ready to go them? I have an idea that they can be the reason of alopecia...
And I there anyone who tried treatment with NAC? I would listen to others opinions...
Sorry for bad English, I am still learning this language ;)
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Comment by Lisa on February 27, 2018 at 1:32pm
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Hi Tatyana,
Welcome to alopecia world and you are doing a great job with your English! I cannot give you any advice about treatments as I have not done any for over twenty years. I have had my alopecia since I was five years old and I am now 61...sooo....I have lived with it a very long time!
I just wanted to say "Welcome" and stay strong and positive! We are very fortunate to have this support sight and I am guessing you have maybe visited NAAF National Alopecia Areata Foundation? Another great means of support!
Take good care!
Lisa
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Comment by Chen on April 12, 2018 at 10:20pm
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How long after starting taking nac, melatonin and selenium did you see results? (first hair growth) Are you taking the 600 mg nac 3x a day, 15 mg melatonin and 55 mcg selenomethionine as recommended by one of the article? Did you take nac for 3 days and stop for 4 days and then resume again?
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Chen, I took nac, melatonin and selenium exactly as recommended by that article you are talking about (600 mg nac 3x a day, 15 mg melatonin and 55 mcg selenomethionine) for fisst 3 months. First results were partial restoring of lunules of nails, I did not have them before, my nails had solid red color without white semicircle. So, they started to restore after 2 weeks of taking medicines. First baby hair growth appeared after 1-1,5 months after started taking medicines. Every month there was a period of intensive growth and period of stopping growth and some aggravation of nails lunules state. But it bacame better and better anyway. After 3 months there were some long pause in improving and I started to take nac every day without breaks. I got amazing results then. Almost all hair were restored. After that in November I got total stop of curing and hair stopped growing and nails start getting worse, So I did not have any improvement still November. I tryed to stop taking all the medicines for 2 weeks (as recommended in that article), but it did not work. But I noticed one more thing. In winter I found out that my prolactin level increased, I took cabergoline for 3 months and last week I notice improvment of my nails, so I expect further improvement. But in the same time, it's spring and still do not know what works - cabergoline or spring :) I was taking nac, melatonin and selenium for whole winter, and I am still taking them. In January I started also active forms of B vitamins (B2, B6, and B12) (thorne methyl guard plus, you can find it on iherb.com), because I read that you should take it in order to make NAC work (it uses methyl forms of B12 and B6 in methylation process).
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I have tried NAC with the melatonin and selenium without success. But nothing has worked for me yet. I did have the lunas return to my nails after taking sulforaphane but no noticeable change in hair growth. I still take the sulforaphane because I feel better on it.
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How long did you try the nac, melatonin and slenomethionine treatment for? Do you have other health and autoimmune issues aside from alopecia areata? Was there improvement in other areas?
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There isn't a universal treatment for this medical condition. Ill people or those who feel weak should take vitamins for a few months. There are individuals who choose to buy medicine from ovitaminpro.com because these products are excellent.
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