I've had Alopecia Universalis for about 3 years now. My dermatologist had started to give me shots in my head, which I very shortly cut out of my visits with him due to the pain it gave me. He gave me methotrexate to see if that would help my immune system get more on track but as anyone with alopecia knows, it seems to be that we are all test rats for whatever meds to take. I also researched this more intense drug called Xeljanz. It was tested on a patient at Yale University who had psoriasis but it really improved his hair over an 8month period more than anything.