Here's an except I just found on some hair research:

The researchers analyzed over many months the changes in the hair growth patterns on shaved mice and rabbits, which indicate cyclic progression between active and quiescent states by stem cells in hair follicles.

"The results are totally surprising. There is complex coordination not apparent to the naked eye," said Cheng-Ming Chuong, professor of pathology at the Keck School and the principal investigator of the study funded by the National Institutes of Health.

The "complex coordination" Chuong refers to is the ability of the large hair stem cell population to communicate with each other to reach robust hair growth, manifesting in a constantly shifting hair wave pattern that often looked like a piece of abstract artwork "painted" on the rabbit's skin.

The scientists found that hair stem cells coordinate their regeneration with each other with the aid of a pair of molecular activator WNT and inhibitor BMP. When WNT and BMP signals are used repetitively among a population of thousands of hair follicles across the entire skin surface, complex regenerative hair growth behavior emerges via the process of self-organization.

The research holds potential for finding a cure for alopecia, or hair loss, by improving the environment for communication. Alopecia occurs in humans partially because stem cells in human hair follicles, unlike those in mice and rabbits, have lost the ability to communicate with each other.

"When each human hair follicle wants to regenerate, it can only count on itself; it's not getting help from other follicles," Chuong said. "But when a rabbit hair follicle regenerates, it can count on two inputs: its own activation, and the activation signal from its neighbors. Rabbits have a very active hair growth, and that is essential for their survival in the wild."

Views: 6

Comment by R0BB on June 19, 2011 at 2:32pm
And .... Braised Rabbit with Cherry Bourbon sauce is AWESOME !!!!

Seriously TG - great post and very informative.

Comment by Tallgirl on June 19, 2011 at 2:35pm
Here's another link for a June 19, 2011 article!!!!

North American Hair Research Society > In The News > Recent ...by D Norris

In The News Recent Meetings Summations Alopecia Areata Research Workshop ... knowledge in three fundamental areas of research in alopecia areata : genetics, ...
www.nahrs.org/home/LinkClick.aspx?link=60&tabid...

This one is fairly technical in language, but also calls for more funding.
Comment by kastababy on June 21, 2011 at 11:21am
Thanks for the information. My only question is, with alopecia research being almost totally defunded with the exception of private donors (and those too are shrinking rapidly by the day), who's going to pay for the follow-up R&D for these studies?

More importantly, why hasn't this been published earlier? This is the type of hidden information that infuriates me 99% of the time. I'll be willing to bet any amount of money it doesn't get mentioned at the "Ask the Experts" panel at the conference this weekend either.

You just gave me an idea for my question.....

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