Alopecia World
www.alopeciaworld.com
Connection between Celiac Disease and AA
I hope that I'm not overstepping our group, but I have CD and AA so feel that I may have important information relating to their connection.
The following is some information I have gathered over the internet regarding their believed connection.
Abstract
Celiac disease is frequently associated with other auto-immune disorders but has never been reported in association with alopecia areata. In a routine clinical practice, 3 patients with such an association were observed. In one of the patients, celiac disease was diagnosed after the occurrence of malabsorption symptoms. In the youngest patient, a 14-year-old boy, glutenfree diet resulted in complete regrowth of scalp and body hair. A prospective screening program for celiac disease using antigliadin and antiendomysial antibodies was therefore set up in 256 consecutive outpatients with alopecia areata. Three patients, all completely asymptomatic for intestinal diseases, were found to be positive and underwent biopsy. Histological analysis showed a flat intestinal mucosa consistent with the diagnosis of celiac disease. The results show that alopecia areata may constitute the only clinical manifestation of celiac disease and that the association between these two conditions is a real one because the observed frequency of association is much greater than can be expected by chance. It is suggested that antigliadin and antiendomysial antibodies should be included in the work-up of patients with alopecia areata.
Copyright © 2003 Elsevier Inc. All rights reserved. Feedback | About Article Finder | Help
Abstract
Background & Aims: The relationship between celiac disease and many autoimmune disorders has been explained by the sharing of a common genetic factor. In a multicenter national study, we examined the relationship between the prevalence of autoimmune disorders in celiac disease and the duration of exposure to gluten. Methods: Over a 6-month period, 909 patients with celiac disease (group A; mean age, 16.1 ± 3.8 years; grouped according to age at diagnosis into three subgroups [group A1, <2 years; group A2, 2-10 years; and group A3, >10 years]), 1268 healthy controls (group B; mean age, 20.8 ± 4.5 years), and 163 patients with Crohn's disease (group C; mean age, 28.8 ± 10 years) were evaluated for the presence of autoimmune disorders. Results: Prevalence of autoimmune disorders in group A was significantly higher than in group B (14% vs. 2.8%; P < 0.000001) but not higher than in group C (12.9%). Prevalence of autoimmune disorders in celiac disease increased with increasing age at diagnosis: 5.1% in group A1, 17% in group A2, and 23.6% in group A3 (P = 0.000001). In group A3, the prevalence of autoimmune disorders was significantly higher than in group C. In a logistic regression model, age at diagnosis was the only significant predictor variable of the odds of developing an autoimmune disorder (r = 0.3; P < 0.000001). Conclusions: Our data show for the first time that the prevalence of autoimmune disorders in celiac disease is related to the duration of exposure to gluten.
Copyright © 2003 Elsevier Inc. All rights reserved. Feedback | About Article Finder | Help
Alopecia Areata And Celiac Disease
Patients With Autoimmune Hair Loss Have A High Rate Of Celiac Disease
By Nancy Lapid, About.com
Updated: April 28, 2008
About.com Health's Disease and Condition content is reviewed by the Medical Review Board
See More About:
celiac disease research
celiac medical issues
celiac disease symptoms
celiac disease diagnosis
Celiac Disease Ads
Gluten Intolerance Symptoms Celiac Disease Symptoms Blood Test for Celiac Disease Celiac Disease and Joint Pain Disease Damages
Celiac disease, an autoimmune disorder, is frequently present in people who also have other autoimmune conditions, such as diabetes, thyroid disease, and autoimmune liver disease. Less well known, however, is an association between celiac disease and alopecia areata.
What Is Alopecia Areata?
Alopecia areata is a condition in which the immune system mistakenly attacks the hair follicles. Alopecia areata usually starts with one or more small, round, smooth bald patches on the head and can eventually cause complete hair loss on the scalp or even on the entire body (a condition known as alopecia universalis).
Alopecia areata usually begins in childhood. It affects males and females equally. Approximately 2% of the population overall, including more than 5 million people in the United States, have alopecia areata.
What Is Known About Alopecia And Celiac Disease?
One of the first research studies linking alopecia with celiac disease was published in 1995. Italian doctors had noticed that several of their patients with alopecia also had celiac disease, and that in one of these patients -- a 14-year-old boy -- the missing hair on his scalp and body completely regrew after he adopted a gluten-free diet. This boy's case, and a few others, prompted the doctors to screen a large group of alopecia patients for celiac disease.
In fact, the doctors did find a relatively high rate of celiac disease in their patients - much greater than could be expected by chance. On the basis of this study, the doctors recommended that celiac disease antibody testing should be performed in all patients with alopecia areata.
Since then, there have been other medical research reports of celiac disease in association with alopecia areata.
Can A Gluten-Free Diet Help Reverse Alopecia Areata?
Unfortunately, there is no cure for alopecia areata. Most, but not all, of the research reports that describe patients with alopecia and celiac disease also report that the patients' hair grew back after they adopted a gluten-free diet. Even in people without celiac disease, however, the course of alopecia is very unpredictable, and sometimes the hair simply grows back by itself.
Where To Get More Information
More information about alopecia areata can be found at The National Alopecia Areata Foundation and The American Academy of Dermatology.
Sources:
Corazza GR et al. Celiac disease and alopecia areata: report of a new association. Gastroenterology 1995; 109:1333-7.
Naveh Y et al. Celiac disease-associated alopecia in childhood. J Pediatr 1999;134:362-4.
Bardella MT et al. Alopecia areata and coeliac disease: no effect of a gluten-free diet on hair growth. Dermatology 2000;200:108-10.
Barbato M et al. Alopecia and coeliac disease: report of two patients showing response to gluten-free diet.
The National Alopecia Areata Foundation
The American Academy of Dermatology.
Symptoms
Typical and Atypical Symptoms of Celiac Disease
Complications of Untreated Celiac Disease
Dermatitis Herpetiformis
Lactose Intolerance and Celiac Disease
Depression and Celiac Disease
/mbiopage.htm/mbiopage.htm
Nancy Lapid
Celiac Disease Guide
Sign up for my Newsletter
My Blog
My Forum
http://www1.mf.uni-lj.si/acta-apa/acta-apa-00-3/papadopoulos.html
Titre du document / Document title
Celiac disease and alopecia areata : report of a new association
Auteur(s) / Author(s)
CORAZZA G. R. (1) ; ANDREANI M. L. ; VENTURO N. ; BERNARDI M. ; TOSTI A. ; GASBARRINI G. ;
Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)
(1) Univ. L'Aquila, dep. internal medicine, L'Aquila, ITALIE
Résumé / Abstract
Celiac disease is frequently associated with other autoimmune disorders but has never been reported in association with alopecia areata. In a routine clinical practice, 3 patients with such an association were observed. In one of the patients, celiac disease was diagnosed after the occurrence of malabsorption symptoms. In the youngest patient, a 14-year-old boy, gluten-free diet resulted in complete regrowth of scalp and body hair. A prospective screening program for celiac disease using antigliadin and antiendomysial antibodies was therefore set up in 256 consecutive outpatients with alopecia areata. Three patients, all completely asymptomatic for intestinal diseases, were found to be positive and underwent biopsy. Histological analysis showed a flat intestinal mucosa consistent with the diagnosis of celiac disease. The results show that alopecia areata may constitute the only clinical manifestation of celiac disease and that the association between these two conditions is a real one because the observed frequency of association is much greater than can be expected by chance. It is suggested that antigliadin and antiendomysial antibodies should be included in the work-up of patients with alopecia areata.
Revue / Journal Title
Gastroenterology ISSN 0016-5085 CODEN GASTAB
Source / Source
1995, vol. 109, no4, pp. 1333-1337 (37 ref.)
Langue / Language
Anglais
Editeur / Publisher
Elsevier, New York, NY, ETATS-UNIS (1943) (Revue)
Mots-clés anglais / English Keywords
Coeliac disease ; Association ; Alopecia decalvans ; Pathophysiology ; Antibody ; Gliadin ; Diagnosis ; Case study ; Human ; Hair (head) ; Digestive diseases ; Intestinal disease ; Intestinal malabsorption ; Immunopathology ; Skin disease ;
Mots-clés français / French Keywords
Coeliaque maladie ; Association ; Pelade décalvante ; Physiopathologie ; Anticorps ; Gliadine ; Diagnostic ; Etude cas ; Homme ; Cheveu ; Appareil digestif pathologie ; Intestin pathologie ; Malabsorption intestinale ; Immunopathologie ; Peau pathologie ;
Mots-clés espagnols / Spanish Keywords
Enfermedad celíaca ; Asociación ; Alopecia decalvans ; Fisiopatología ; Anticuerpo ; Gliadina ; Diagnóstico ; Estudio caso ; Hombre ; Cabello ; Aparato digestivo patología ; Intestino patología ; Malabsorción intestinal ; Inmunopatología ; Piel patología ;
Localisation / Location
INIST-CNRS, Cote INIST : 2090, 35400005005062.0380
Copyright 2008 INIST-CNRS. All rights reserved
Toute reproduction ou diffusion même partielle, par quelque procédé ou sur tout support que ce soit, ne pourra être faite sans l'accord préalable écrit de l'INIST-CNRS.
No part of these records may be reproduced of distributed, in any form or by any means, without the prior written permission of INIST-CNRS.
Nº notice refdoc (ud4) : 3684027
http://www.stopnowhairloss.com/2008/02/05/alopecia-areata-can-be-ca...
http://www.nutramed.com/celiac/celiacdisease.htm
http://en.wikipedia.org/wiki/Gluten-sensitive_enteropathy_associate...
The following is some information I have gathered over the internet regarding their believed connection.
Abstract
Celiac disease is frequently associated with other auto-immune disorders but has never been reported in association with alopecia areata. In a routine clinical practice, 3 patients with such an association were observed. In one of the patients, celiac disease was diagnosed after the occurrence of malabsorption symptoms. In the youngest patient, a 14-year-old boy, glutenfree diet resulted in complete regrowth of scalp and body hair. A prospective screening program for celiac disease using antigliadin and antiendomysial antibodies was therefore set up in 256 consecutive outpatients with alopecia areata. Three patients, all completely asymptomatic for intestinal diseases, were found to be positive and underwent biopsy. Histological analysis showed a flat intestinal mucosa consistent with the diagnosis of celiac disease. The results show that alopecia areata may constitute the only clinical manifestation of celiac disease and that the association between these two conditions is a real one because the observed frequency of association is much greater than can be expected by chance. It is suggested that antigliadin and antiendomysial antibodies should be included in the work-up of patients with alopecia areata.
Copyright © 2003 Elsevier Inc. All rights reserved. Feedback | About Article Finder | Help
Abstract
Background & Aims: The relationship between celiac disease and many autoimmune disorders has been explained by the sharing of a common genetic factor. In a multicenter national study, we examined the relationship between the prevalence of autoimmune disorders in celiac disease and the duration of exposure to gluten. Methods: Over a 6-month period, 909 patients with celiac disease (group A; mean age, 16.1 ± 3.8 years; grouped according to age at diagnosis into three subgroups [group A1, <2 years; group A2, 2-10 years; and group A3, >10 years]), 1268 healthy controls (group B; mean age, 20.8 ± 4.5 years), and 163 patients with Crohn's disease (group C; mean age, 28.8 ± 10 years) were evaluated for the presence of autoimmune disorders. Results: Prevalence of autoimmune disorders in group A was significantly higher than in group B (14% vs. 2.8%; P < 0.000001) but not higher than in group C (12.9%). Prevalence of autoimmune disorders in celiac disease increased with increasing age at diagnosis: 5.1% in group A1, 17% in group A2, and 23.6% in group A3 (P = 0.000001). In group A3, the prevalence of autoimmune disorders was significantly higher than in group C. In a logistic regression model, age at diagnosis was the only significant predictor variable of the odds of developing an autoimmune disorder (r = 0.3; P < 0.000001). Conclusions: Our data show for the first time that the prevalence of autoimmune disorders in celiac disease is related to the duration of exposure to gluten.
Copyright © 2003 Elsevier Inc. All rights reserved. Feedback | About Article Finder | Help
Alopecia Areata And Celiac Disease
Patients With Autoimmune Hair Loss Have A High Rate Of Celiac Disease
By Nancy Lapid, About.com
Updated: April 28, 2008
About.com Health's Disease and Condition content is reviewed by the Medical Review Board
See More About:
celiac disease research
celiac medical issues
celiac disease symptoms
celiac disease diagnosis
Celiac Disease Ads
Gluten Intolerance Symptoms Celiac Disease Symptoms Blood Test for Celiac Disease Celiac Disease and Joint Pain Disease Damages
Celiac disease, an autoimmune disorder, is frequently present in people who also have other autoimmune conditions, such as diabetes, thyroid disease, and autoimmune liver disease. Less well known, however, is an association between celiac disease and alopecia areata.
What Is Alopecia Areata?
Alopecia areata is a condition in which the immune system mistakenly attacks the hair follicles. Alopecia areata usually starts with one or more small, round, smooth bald patches on the head and can eventually cause complete hair loss on the scalp or even on the entire body (a condition known as alopecia universalis).
Alopecia areata usually begins in childhood. It affects males and females equally. Approximately 2% of the population overall, including more than 5 million people in the United States, have alopecia areata.
What Is Known About Alopecia And Celiac Disease?
One of the first research studies linking alopecia with celiac disease was published in 1995. Italian doctors had noticed that several of their patients with alopecia also had celiac disease, and that in one of these patients -- a 14-year-old boy -- the missing hair on his scalp and body completely regrew after he adopted a gluten-free diet. This boy's case, and a few others, prompted the doctors to screen a large group of alopecia patients for celiac disease.
In fact, the doctors did find a relatively high rate of celiac disease in their patients - much greater than could be expected by chance. On the basis of this study, the doctors recommended that celiac disease antibody testing should be performed in all patients with alopecia areata.
Since then, there have been other medical research reports of celiac disease in association with alopecia areata.
Can A Gluten-Free Diet Help Reverse Alopecia Areata?
Unfortunately, there is no cure for alopecia areata. Most, but not all, of the research reports that describe patients with alopecia and celiac disease also report that the patients' hair grew back after they adopted a gluten-free diet. Even in people without celiac disease, however, the course of alopecia is very unpredictable, and sometimes the hair simply grows back by itself.
Where To Get More Information
More information about alopecia areata can be found at The National Alopecia Areata Foundation and The American Academy of Dermatology.
Sources:
Corazza GR et al. Celiac disease and alopecia areata: report of a new association. Gastroenterology 1995; 109:1333-7.
Naveh Y et al. Celiac disease-associated alopecia in childhood. J Pediatr 1999;134:362-4.
Bardella MT et al. Alopecia areata and coeliac disease: no effect of a gluten-free diet on hair growth. Dermatology 2000;200:108-10.
Barbato M et al. Alopecia and coeliac disease: report of two patients showing response to gluten-free diet.
The National Alopecia Areata Foundation
The American Academy of Dermatology.
Symptoms
Typical and Atypical Symptoms of Celiac Disease
Complications of Untreated Celiac Disease
Dermatitis Herpetiformis
Lactose Intolerance and Celiac Disease
Depression and Celiac Disease
/mbiopage.htm/mbiopage.htm
Nancy Lapid
Celiac Disease Guide
Sign up for my Newsletter
My Blog
My Forum
http://www1.mf.uni-lj.si/acta-apa/acta-apa-00-3/papadopoulos.html
Titre du document / Document title
Celiac disease and alopecia areata : report of a new association
Auteur(s) / Author(s)
CORAZZA G. R. (1) ; ANDREANI M. L. ; VENTURO N. ; BERNARDI M. ; TOSTI A. ; GASBARRINI G. ;
Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)
(1) Univ. L'Aquila, dep. internal medicine, L'Aquila, ITALIE
Résumé / Abstract
Celiac disease is frequently associated with other autoimmune disorders but has never been reported in association with alopecia areata. In a routine clinical practice, 3 patients with such an association were observed. In one of the patients, celiac disease was diagnosed after the occurrence of malabsorption symptoms. In the youngest patient, a 14-year-old boy, gluten-free diet resulted in complete regrowth of scalp and body hair. A prospective screening program for celiac disease using antigliadin and antiendomysial antibodies was therefore set up in 256 consecutive outpatients with alopecia areata. Three patients, all completely asymptomatic for intestinal diseases, were found to be positive and underwent biopsy. Histological analysis showed a flat intestinal mucosa consistent with the diagnosis of celiac disease. The results show that alopecia areata may constitute the only clinical manifestation of celiac disease and that the association between these two conditions is a real one because the observed frequency of association is much greater than can be expected by chance. It is suggested that antigliadin and antiendomysial antibodies should be included in the work-up of patients with alopecia areata.
Revue / Journal Title
Gastroenterology ISSN 0016-5085 CODEN GASTAB
Source / Source
1995, vol. 109, no4, pp. 1333-1337 (37 ref.)
Langue / Language
Anglais
Editeur / Publisher
Elsevier, New York, NY, ETATS-UNIS (1943) (Revue)
Mots-clés anglais / English Keywords
Coeliac disease ; Association ; Alopecia decalvans ; Pathophysiology ; Antibody ; Gliadin ; Diagnosis ; Case study ; Human ; Hair (head) ; Digestive diseases ; Intestinal disease ; Intestinal malabsorption ; Immunopathology ; Skin disease ;
Mots-clés français / French Keywords
Coeliaque maladie ; Association ; Pelade décalvante ; Physiopathologie ; Anticorps ; Gliadine ; Diagnostic ; Etude cas ; Homme ; Cheveu ; Appareil digestif pathologie ; Intestin pathologie ; Malabsorption intestinale ; Immunopathologie ; Peau pathologie ;
Mots-clés espagnols / Spanish Keywords
Enfermedad celíaca ; Asociación ; Alopecia decalvans ; Fisiopatología ; Anticuerpo ; Gliadina ; Diagnóstico ; Estudio caso ; Hombre ; Cabello ; Aparato digestivo patología ; Intestino patología ; Malabsorción intestinal ; Inmunopatología ; Piel patología ;
Localisation / Location
INIST-CNRS, Cote INIST : 2090, 35400005005062.0380
Copyright 2008 INIST-CNRS. All rights reserved
Toute reproduction ou diffusion même partielle, par quelque procédé ou sur tout support que ce soit, ne pourra être faite sans l'accord préalable écrit de l'INIST-CNRS.
No part of these records may be reproduced of distributed, in any form or by any means, without the prior written permission of INIST-CNRS.
Nº notice refdoc (ud4) : 3684027
http://www.stopnowhairloss.com/2008/02/05/alopecia-areata-can-be-ca...
http://www.nutramed.com/celiac/celiacdisease.htm
http://en.wikipedia.org/wiki/Gluten-sensitive_enteropathy_associate...
Replies to This Discussion
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Permalink Reply by Georgie on
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I would have to say that eliminating gluten from the diet has had some positive effects for you! I've been gluten free for several weeks so far and my pants fit better! ;)
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Permalink Reply by Stacey Owen on
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So I have been lactose intolerant my whole life... Are you guys saying that it could be my alopecia? And this is kinda embarrassing but when you talk about stomach issues...I have a MAJOR problem with loud abrupt burps out of no where. I have done it my whole life but it is recently getting really bad! I'm going Thursday for a dr opinion. Could this be associated with alopecia? That's cray to even think about ti me. Lol
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Permalink Reply by Jessica on
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Hi All,
I too have AA and Celiac's disease i just found out 2 days ago. For months now i have had all sorts of problems not know what it was, a friend of mine told me of the possible connection of the 2 so i was tested.
I started to eat a gluten free diet Jan 1st and am having a hard time finding good food anyone know of places to get some yummy gluten free food?
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Permalink Reply by Eileen Simpson on
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I Jessica,
Yes I know all kinds of places for you lots of online stores, but Wal-Mart carries a some really a lot of foods that are GF. Not the noodles, put sauces and such.
This is a link to Delphi Forum: http://www.delphiforums.com/ once you register you can go to message boards then to the left you will see health and wellness click there and you will see a Celiac Disease section click then your there. Introduce yourself as being new to CD and you will get all kinds of help. Chin up there are worse things like not knowing you have it and dieing of weird autoimmune disease. So rejoice and be happy you now know what's wrong. It can be difficult believe me I've been there so I often avoid food gatherings, or bring my own. Just remember to ask questions and don't eat anything that you don't know what it's made from or of.
They really halped me with all that I needed to know. It will help you also. You will need to register much like this group but they are geared for CD Celiac Disease. Do you have help from your doctor? Probably a good idea is to call different health food stores to see what they offer and like I said there is so much online that are really great places.
Please try the link to Delphi Forum and try to see if there is a group nearby. If you let me know about where you are as far as location I will try to see what I can find out for in person support groups. They really are importand, not all are the same, but most are very helpful.
If I can help you in any other way please write.
Eileen
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Permalink Reply by Joel on
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Thanks A Lot Polly G. !!!! First I have to give up wheat and now all edible prepared anything (has gluten in it) and now you throw in dairy so i cant even eat cheese, and beer has barley ( a very wheat like weed ) AAAHHHHHHH the future sucks with or without hair!!!!!! Just kidding thanks for the info and again a fascinating scenario. Before this started I had really really bad stomach / gut stress related pain etc...
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Joel you might be interested to know about a book called the Gluten-Free Grocery Shopping Guide. I have the 2008-2009 format, but there is a new one also. The book allows us to know which products are ok in the general population world.
Thanks I'm glad this Blog was a help to people.
Eileen
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I am fortunate to have one local but they do internet sales. I'm sure you can find one closer to you. Mine is called "Sunny Valley Wheat Free" maple Valley WA.
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Permalink Reply by Tamara Dixon on
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I found a really good cookbook on amazon called the gluten free vegan, I have tried a few recipes and they were really good. Check it out.
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Permalink Reply by Andrea on
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so you can have Celiac without any intestional issues?? How does someone get tested for celiac? I've heard it is hereditary...is that true? Not sure if anyone in my family has Celiac or not. I really don't want to put my 5 yr. old daughter through a bunch of testing if she doesn't need it.
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Yes you can have Celiac Disease without any intestional issues. You ask your doctor for a Celiac blood test pretty simple really. Here is home test that you might find interesting and useful. There is other valuable information within these pages as well. http://celiachometest.com/
Good luck to you.
Eileen
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Permalink Reply by Rahela on
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hi im rachel from croatia i have alopecia all my life :( since i had 6 y. now im 27 im interesting for this disscusion couse i have big gastro problems since i was married 7 years ago ...probably couse i changed my way of eating... since then i had big inestional issues like bloting and abdomenal pain and last week i made food intolerance test and thay find me high senistive on egg white, and moderate senitive on yolk, soya wheat, rice corn ,milk, ananas ,barley, since than i made research on internet and i found connection between alopecia and food .I was talking with my nutricionist advisor yesterday and she told me that i should make celiac test and i order home test kit it's not expensive and u can test youself at home , if it's positive than u have celiac if's not you can still have celiac.. .. and also u can have celiac all ur life without knowlege and without any intestional issues....but i found many artical related betwen celiac and gluten free and casein free diat and people solve their problems with alopecia ..so from now on im on strickly grluten and casein free diet and i will write about my improvement;)
good luck to everybody ..and sorry becasue my english ;(
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