New Clinical Trial - PF-06651600

Anyone taking part or heard of the Pfizer Clinical trial in phase 2B/3?  I have alopecia and it got really bad over the last year - likely due to stress and bad sleeping habits.  Within a span of 2-3 weeks I was losing hair rapidly - lost all my eyebrow hair, eyelashes etc.  


I have been approached to take part in the trial but am worried about the potential side effects (this is likely a JAK2 or JAK3 drug).  They say that this is supposed to be 'better' then tofa but again, unsure if I want to take part.

I am just contemplating the pro's vs the cons..... i.e. - internally im a healthy 36 year old male... externally - i really want my eyebrows back and the psychological impact that alopecia has is annoying!

Thoughts?

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Permalink Reply by chris_s on October 3, 2019 at 10:25am

I have no input, but are you sure you have the drug name/number correct? there are a few with similar names, and the one you posted isn't turning up any google results


Generally these trials are very closely supervised so the risk is low. Especially at a phase 2b/3

thanks!

edit: I suspect you meant PF-06651600

Permalink Reply by AM on October 3, 2019 at 2:37pm

You're right it is PF-06651600!...

Permalink Reply by Nor75 on October 4, 2019 at 3:38pm

In appr three years we will all be treated PF-06651600. It is the breakthrough med.

Permalink Reply by AM on October 4, 2019 at 3:44pm

Thanks - did you read this somewhere?  I was speaking to a derm yesterday who mentioned the same thing?

Permalink Reply by Nor75 on October 7, 2019 at 6:50am

This is not a new trial. The medication is in development since 2016 and will

expectedly be marketed in 2022. In the trials nobody had any side effects.

It will be the standard treatment for AA.

Permalink Reply by kevin on October 7, 2019 at 5:18pm

hello nor there is also the ctp 543 and he a step ahead and better result against I doubt that it is in 2022 because there is still a test phase is the last phase 3 I say more 2024 if all is well. ctp 543 is a derivative of ruxolitinib and jak to pfizer that of xeljanz.

Permalink Reply by AM on October 12, 2019 at 7:41pm

Do you know if JAKs can impact conceiving or pregnancies?

Permalink Reply by mtran2000 on January 12, 2020 at 6:34am

Sounds promising but I hope we don't have to wait until 2024 for it to come out.

Permalink Reply by Fingers_Crossed on October 4, 2019 at 6:00pm

There is someone on the xeljanz thread who is in this trial. Cassidymain . You could reach out to them for more information.  The side effects and risks that one is willing to take is such a personal decision. Personally, I would do anything for my hair.  I would take the side effects of jak inhibitors any day over being bald. 

Permalink Reply by AM on December 8, 2019 at 8:05pm

Hi All  - i started the trial last week.  Although this is a double blind trial - i think I do have some meds as 1 of the tablets taste a lot different then the others :)... 


How long did it take for people to start to see any growth? Week 1 is done !

Permalink Reply by Fuzzless on January 7, 2020 at 3:31pm

Hi!  How is the trial going for you?  Any side effects?

Permalink Reply by Apple on January 11, 2020 at 12:10pm

HI THERE, HOW DID IT GO? DID YOU DECIDE? I WOULD LIKE TO HEAR MORE ABOUT IT, VERY INGENIOUS OF PFIZER.

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