Alopecia World
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Xeljanz (Tofacitinib Citrate): My experience on the trial
I have received a lot of interest from others on here in my involvement with the Xeljanz trials at Yale.
I thought it would be nice for everyone if I documented my progress on here.
Xeljanz is a Jak3 inhibitor and is believed to work with alopecia by turning off the distress signal relayed by the hair follicle to the attacking immune system which is the cause of the hairs falling out. Xeljanz comes in a strength of 5mg per pill and a full box contains 60 tablets. The recommended dosage for arthritis is 1 tablet in the morning and another in the evening each day.
The trial is set in a series of stages and there are requirements before participating. These include monthly visits and blood tests every 2 weeks. Dr Brett King is absolutely fantastic and is an inspiration to me. His positivity and enthusiasm gives me the much needed hope I have craved for over a decade. I have been put on a low dose to start with which is 1 tablet every other day. My dosage has now been increased to 1 tablet every day and next month it could be increased to 2 tablets per day depending on the results.
I have completed my first month and have already noticed my alopecia has stabilised . I have not lost any existing hairs. In addition to this I have seen little hairs growing in my chest area as well as eyebrows. Fingers crossed! To date, I have experienced no side effects.
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AW: Other discussions on Xeljanz / Tofacitinib
https://alopeciaworld.com/main/search/search?q=Tofacitinib
Replies to This Discussion
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Permalink Reply by AlopeciaDestroyedMyLife on
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I will put updates up each month , next update will be in a week and a half.
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Permalink Reply by macdev on
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hello,
"Aquovel"( for dogs) is not jet available in France...and I think it will be 'cheaper" than Xeljanz..
I'm waiting for...
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Hi,
Update coming next week .
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Permalink Reply by manuel j. torres on
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Hey hope all is well,
Wondering if you're shaving as they grow? I'm contemplating if i should or not
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Cause they're all over the place... There're not going to grow evenly.. Well, they're not for me
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Permalink Reply by cws on
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I am just giving an update on my progress with Xeljanz. I have been on 5mg per day (which is 1/2 the recommended dosage) for the past month and have had no side effects. However, I have not had much hair growth either...which was expected given the dosage I have been on. I have seen a decent amount of vellus hair growth at my eyebrows. I am starting the recommended dosage today and am cautiously optimistic about my results for this upcoming month. The half-life if this drug is 3hrs and anyone with AU will likely not see much in the way of results until they take 10mg per day. I am AU. I started out at half dosage for safety reasons and wanted to make sure I did not have sever side effects.
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hello,
"Aquovel"( for dogs) is not jet available in France...and I think it will be 'cheaper" than Xeljanz..
I'm waiting for...