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Xeljanz (Tofacitinib Citrate): My experience on the trial
I have received a lot of interest from others on here in my involvement with the Xeljanz trials at Yale.
I thought it would be nice for everyone if I documented my progress on here.
Xeljanz is a Jak3 inhibitor and is believed to work with alopecia by turning off the distress signal relayed by the hair follicle to the attacking immune system which is the cause of the hairs falling out. Xeljanz comes in a strength of 5mg per pill and a full box contains 60 tablets. The recommended dosage for arthritis is 1 tablet in the morning and another in the evening each day.
The trial is set in a series of stages and there are requirements before participating. These include monthly visits and blood tests every 2 weeks. Dr Brett King is absolutely fantastic and is an inspiration to me. His positivity and enthusiasm gives me the much needed hope I have craved for over a decade. I have been put on a low dose to start with which is 1 tablet every other day. My dosage has now been increased to 1 tablet every day and next month it could be increased to 2 tablets per day depending on the results.
I have completed my first month and have already noticed my alopecia has stabilised . I have not lost any existing hairs. In addition to this I have seen little hairs growing in my chest area as well as eyebrows. Fingers crossed! To date, I have experienced no side effects.
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AW: Other discussions on Xeljanz / Tofacitinib
https://alopeciaworld.com/main/search/search?q=Tofacitinib
Replies to This Discussion
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Permalink Reply by Patchesforlife on
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Ok I admit I just went and purchased some American gingseng.... wonder if it's ok to take with xeljanz? Wonder how much humans should take? I ordered it online... it'll probably get to me and I'll read the label and it will say "do not take with jack inhibitors" lol.
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i have spots on my lower legs for about 12 years.no other places. my daughter has vitiligo on the same place. her lower legs?why?
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That is so exciting! I am so new to all of this and am sad and scared. All of my body hair is gone and now the hair on my head is almost all gone too. I am sick over it - I know it is only hair but I have had long, thick beautiful hair my entire life. This is terrifying. Good luck to you as you bring me hope.
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Just remember new therapies and possible cures are on the horizon. Gene therapy is gaining ground and autoimmune is an area of interest for them to explore with it. I have been disappointed in progress with stem cells...I am hoping there is more interest with gene therapy.
It is just hair...but I also know it's disfiguring. I have been on Xeljanz for 2+ yrs to fight it. I never got everything back but I got enough to be ok with it.
Best of luck.
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I just researched it a bit. You are not likely to get a response from it. The problem is your body is turning on itself because there is a particular protein in the dermal sheath of your hair that it has now decided to attack. I don't think that product is going to help circumvent that issue. If it really worked, we would all be on it.
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Do you have any information regarding gene therapy? I learned that university of Queensland is having trial for Gene therapy. Thanks
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Jeanne! I get you girl! I got a spot last December- all gone by July, then my lashes and eyebrows went....I'm still in a state of suspended terror. I hate not recognising my familiar face in the mirror, wearing a wig means no breeze ton my head- I miss that too. I'm on xeljanz now 4 months- it's slow - I'm gonna do steroid pulsing to help. Just rest assured others feel like you and "it's just hair" is often not helpful to hear!
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hs anyone tried to v take turmeric and quercitin supplements?
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