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Xeljanz (Tofacitinib Citrate): My experience on the trial
I have received a lot of interest from others on here in my involvement with the Xeljanz trials at Yale.
I thought it would be nice for everyone if I documented my progress on here.
Xeljanz is a Jak3 inhibitor and is believed to work with alopecia by turning off the distress signal relayed by the hair follicle to the attacking immune system which is the cause of the hairs falling out. Xeljanz comes in a strength of 5mg per pill and a full box contains 60 tablets. The recommended dosage for arthritis is 1 tablet in the morning and another in the evening each day.
The trial is set in a series of stages and there are requirements before participating. These include monthly visits and blood tests every 2 weeks. Dr Brett King is absolutely fantastic and is an inspiration to me. His positivity and enthusiasm gives me the much needed hope I have craved for over a decade. I have been put on a low dose to start with which is 1 tablet every other day. My dosage has now been increased to 1 tablet every day and next month it could be increased to 2 tablets per day depending on the results.
I have completed my first month and have already noticed my alopecia has stabilised . I have not lost any existing hairs. In addition to this I have seen little hairs growing in my chest area as well as eyebrows. Fingers crossed! To date, I have experienced no side effects.
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Replies to This Discussion
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Permalink Reply by Rach1992 on
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Nah man, I'd still say that's shallow. It's okay, though. I'd say we're all shallow about specific things- that's human nature. I've never cared if a guy had hair or not (and like I said I had a ton of hair) but I've always been shallow about a guy being overweight. I would never date a guy a few pounds too heavy.
Yeah, that's true- the plane ride would be tough. I wouldn't want to risk it in general, though. It's "unlikely" but it's more likely than the likelihood was to get alopecia!
And yeah I see that but I've always thought that professional help would be more useful than getting the hair back for the big issue of self esteem. This is most DEFINITELY going to be an unpopular opinion here but I'd say it's like getting a nose job for a big ole wonky nose vs. going to a therapist to accept the nose you have. Getting a nose job is even cheaper and lower risk than Xeljanz though. I agree that it's what it comes down to. I just want everyone to be happy. It would definitely be easier if more people were aware of alopecia and didn't ostracize people for it!
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Permalink Reply by sadele on
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6 months on xeljanz, 2 weeks with added 100mg plaquenil. Kenellog shots every 4 weeks for 3 months.
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Permalink Reply by Xeljanzmiracle on
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Great Serinaadele! Its interesting how our regrowth patterns are so similar. More hair on the crown, less in certain areas, the same resistant bald spots, etc. Our heads look about the same right now. I'm on month 5, ur a little bit ahead of me.
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Permalink Reply by Hilda on
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Hello dear serinaadele
Congratulations for your amazing progress!
I just want to know howmany mg of the xeljanz did you use during those 6 months and also howmany are you using already?
Who's your doctor?
Pleaseeeee tell me im begging you to answer my questions as soon as you can
As you said hair for me is like heart so pleas let me know
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Back of head
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This sides are still really bare and the hair itself is very thin compared to what I had before I lost it all. My hair was my "signature", I would say. My safety blanket. So losing it was very difficult for me.. But I known it is for all of us.
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Permalink Reply by Joao Piva on
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I can imagine how much difficult it is for a woman. For men is not that hard, but I had nails problem also and the lack of eyebrow makes me look strange. I started to use glasses even without much need.
As I see your hair is coming back well, don´t worry.
I still have some hairless spots in my head, and it seems that they won´t go away if I don´t start with a higher dosage. I´m waiting my doctor´s directions. My blood works are very well, thanks god.
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Top: December of 2006
Bottom: March of 2007
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Some of my male and female friends encouraged me to "stay bald" cause they like how my features stand out more. You are another one Joao. You look good with or without hair. Your eyes really stand out.
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Thanks for the complement.
Is very important for me to avoid getting fat.
With or without hair. Rsrsrs
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I was talking about your face and your head, lol! Your eyes stand out more because of the baldness. Bald IS BEAUTIFUL on many individuals. Just when I was getting used to it, had accepted it for myself, and theown most of my wigs away, I got approved for Xeljanx, lol! So, if I can't medically or financially, afford to stay on it in the future, I learned that many people thought I was beautiful bald and had an ideal head shape,etc. Who would have known? I hid my baldness for 5 years with wigs because I thought people would think I looked like a MONSTER. I was shocked and amused to when complete strangers on the street would stop and tell me I was beautiful and they "loved my hairstyle" lol!
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