Xeljanz (Tofacitinib Citrate): My experience on the trial

I have received a lot of interest from others on here in my involvement with the Xeljanz trials at Yale.

I thought it would be nice for everyone if I documented my progress on here. 

Xeljanz is a Jak3 inhibitor and is believed to work with alopecia by turning off the distress signal relayed by the hair follicle to the attacking immune system which is the cause of the hairs falling out. Xeljanz comes in a strength of 5mg per pill and a full box contains 60 tablets. The recommended dosage for arthritis is 1 tablet in the morning and another in the evening each day.

The trial is set in a series of stages and there are requirements before participating. These include monthly visits and blood tests every 2 weeks. Dr Brett King is absolutely fantastic and is an inspiration to me. His positivity and enthusiasm gives me the much needed hope I have craved for over a decade. I have been put on a low dose to start with which is 1 tablet every other day. My dosage has now been increased to 1 tablet every day and next month it could be increased to 2 tablets per day depending on the results. 

I have completed my first month and have already noticed my alopecia has stabilised . I have not lost any existing hairs. In addition to this I have seen little hairs growing in my chest area as well as eyebrows. Fingers crossed! To date, I have experienced no side effects.

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Related Post on Alopecia World:  

Xeljanz / Tofacitinib

Olumiant

Jak Inhibitors

 

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Replies to This Discussion

Permalink Reply by ksp2276 on November 25, 2015 at 10:19pm

Would you want to meet up? I would love to hear about your feelings on xeljanz and Dr. bordone

Permalink Reply by serg navaro on November 27, 2015 at 1:25pm
Just completed 3 months on xeljanz and started my 4th bottle today :) staying hopeful
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Permalink Reply by Jcortez05 on November 27, 2015 at 1:38pm
When did you start noticing growth
Permalink Reply by serg navaro on November 27, 2015 at 3:56pm
Around a month and a half
Permalink Reply by dr. who on November 27, 2015 at 5:11pm

thanks for the pic, how many pills are you taking per day?

Permalink Reply by serg navaro on November 27, 2015 at 5:21pm
2 per day
Permalink Reply by inggare on November 28, 2015 at 5:46pm
hello ,to you of adverse reaction? keep us informed of the result.thank you .
Permalink Reply by Jckah on November 28, 2015 at 6:41pm
Tuesday marks 20 weeks. I'd say my scalp is at 100% now, the resistant spots started to get fuzzy this week. I developed a respiratory tract infection this week but my body fought it off within 2 days, no biggie, otherwise I feel good. Acne is starting to clear up too.
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Permalink Reply by dr. who on November 28, 2015 at 6:54pm

cool, it looks great, happy for you , how many pills are you taking right now? have you change the dosage since you started?

Permalink Reply by Jckah on November 28, 2015 at 7:32pm
Thanks! I've been on 2 pills a day since day 1
Permalink Reply by singh on November 28, 2015 at 8:44pm
Wow absolutely beautiful ! So happy for you :) !!
Permalink Reply by marisa on November 29, 2015 at 9:04pm
So happy for you...can you please post a before and present pic....im curious on your progress. Who is your dr?

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