Xeljanz (Tofacitinib Citrate): My experience on the trial

I have received a lot of interest from others on here in my involvement with the Xeljanz trials at Yale.

I thought it would be nice for everyone if I documented my progress on here. 

Xeljanz is a Jak3 inhibitor and is believed to work with alopecia by turning off the distress signal relayed by the hair follicle to the attacking immune system which is the cause of the hairs falling out. Xeljanz comes in a strength of 5mg per pill and a full box contains 60 tablets. The recommended dosage for arthritis is 1 tablet in the morning and another in the evening each day.

The trial is set in a series of stages and there are requirements before participating. These include monthly visits and blood tests every 2 weeks. Dr Brett King is absolutely fantastic and is an inspiration to me. His positivity and enthusiasm gives me the much needed hope I have craved for over a decade. I have been put on a low dose to start with which is 1 tablet every other day. My dosage has now been increased to 1 tablet every day and next month it could be increased to 2 tablets per day depending on the results. 

I have completed my first month and have already noticed my alopecia has stabilised . I have not lost any existing hairs. In addition to this I have seen little hairs growing in my chest area as well as eyebrows. Fingers crossed! To date, I have experienced no side effects.

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AW:  Other discussions on Xeljanz / Tofacitinib

https://alopeciaworld.com/main/search/search?q=Tofacitinib

 

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Permalink Reply by Peachfuzz on March 18, 2016 at 6:31pm

Specialists tell me you need to apply the cream for at least 3 months to see results

Permalink Reply by Denise on March 18, 2016 at 8:40pm

Hello everyone, and congratulations to others with growth, I have been on the XELJANZ for a month. I  see a light hair on sections of my head. I have been taking injections for my eyebrows, I have had a total of 4, once a month and most of my eyebrows have grow back. I feel little pubic hairs growing back as well, I hope I don't offend anyone but I this it's important too. Still no eye lashes. So wish everyone the very best, I have been very emotional lately. I just ended a 13 year relationship, it's not because of alopecia, but it here me see people for what they are really about. Oh well So I am single now ready to mingle. I am kind of nervous because I just don't feel attractive, wish me luck.

Permalink Reply by Xeljanz2015 on March 18, 2016 at 10:18pm
Denise, give yourself time and you'll find the right person! Dedicate time to yourself and I hope you respond really well to Xeljanz!
Permalink Reply by Xeljanzmiracle on March 19, 2016 at 10:58am
Denise CONGRATULATIONS. You are on your way! You have regrown hair in a month! Just so you know, it will be whitish blonde at first and stick out like a porcupine. Then the hairs start turning darker and getting longer. I'm not sure what your original color was. I didn't see any eyelashes for a couple of months and some of them came in blonde and some were dark. I have most of my top lashes back now and some bottom ones. Please keep us updated on your progress. Where do you live? And how did you get your Xeljanz?
Permalink Reply by sultan h on March 19, 2016 at 11:39am
That's awesome . keep going Denise
and give us your updating .
I'm gonna to get my first Xeljanz on Monday
March 21 hope I get good results soon
pray to me . have good day guys
Permalink Reply by Xeljanzmiracle on March 19, 2016 at 3:41pm
Wish you the best Sultan h!
Permalink Reply by Xeljanz2015 on March 18, 2016 at 10:14pm
Peachfuzz I have enough cream for at least 2 more months I think, so by then I'll know if it's worth it to buy more or not. Cross fingers! I would love to have my eyebrows back. It makes a huge difference!
Permalink Reply by Peachfuzz on March 19, 2016 at 7:36am

I am on  trial now of topical Rux and Xel, i'll be finished with the cream at the end of April (3 months)

the specialists have told me they have had positive and non respond in the results, let's see what happens

Permalink Reply by Xeljanzmiracle on March 19, 2016 at 10:45am
So Peachfuzz, are you putting the Topical R on your eyebrows? Are you taking the Xeljanz orally or topically? If orally, how much a day? Who are the Specialists?
Permalink Reply by Peachfuzz on March 19, 2016 at 5:10pm

I am putting topical R and X plus 2 placebo creams on my eyebrows and sideburns. I don't know which cream is which, its deliberately random, applying twice a day. Hope I will get a reation then take it from there, if not I may consider oral X, I am currently not on oral X, I don't live in the US so I may not get copay. The specialists are a private skin clinic in Australia 

Permalink Reply by Xeljanzmiracle on March 19, 2016 at 5:36pm
Thanks. Did they assign different creams to different areas so they will know what worked or didn't? It sounds like 4 different creams right?
Permalink Reply by Peachfuzz on March 19, 2016 at 5:42pm

Yes, 4 different creams to different areas. It takes over 3 months to see any reation, the specialists told me some trailists have seen results some not. End of April will be the end of 3 months for me

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