Xeljanz (Tofacitinib Citrate): My experience on the trial

I have received a lot of interest from others on here in my involvement with the Xeljanz trials at Yale.

I thought it would be nice for everyone if I documented my progress on here. 

Xeljanz is a Jak3 inhibitor and is believed to work with alopecia by turning off the distress signal relayed by the hair follicle to the attacking immune system which is the cause of the hairs falling out. Xeljanz comes in a strength of 5mg per pill and a full box contains 60 tablets. The recommended dosage for arthritis is 1 tablet in the morning and another in the evening each day.

The trial is set in a series of stages and there are requirements before participating. These include monthly visits and blood tests every 2 weeks. Dr Brett King is absolutely fantastic and is an inspiration to me. His positivity and enthusiasm gives me the much needed hope I have craved for over a decade. I have been put on a low dose to start with which is 1 tablet every other day. My dosage has now been increased to 1 tablet every day and next month it could be increased to 2 tablets per day depending on the results. 

I have completed my first month and have already noticed my alopecia has stabilised . I have not lost any existing hairs. In addition to this I have seen little hairs growing in my chest area as well as eyebrows. Fingers crossed! To date, I have experienced no side effects.

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Related Post on Alopecia World:  

Xeljanz / Tofacitinib

Olumiant

Jak Inhibitors

 

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Permalink Reply by sultan h on October 28, 2016 at 12:35pm
how was it going with 4 pills sadele?
Permalink Reply by Xeljanzmiracle on October 28, 2016 at 1:07pm
Good news everyone! Pfizer's pharmacy called me this morning and they are now dispensing Xeljanz for 3 MONTHS AT A TIME, instead of one. I asked the lady why and she said "it will cut down on number of phone calls to reorder."
Permalink Reply by James 2me on October 28, 2016 at 3:40pm
Yes Xelljanzmiracle that was how mine was received last week 3 bottles 11mgs I am currently in the process of being reevaluated for another year with Sonexos pharmacy hopefully I will be approved again. Have you ever had any health issues. My white cell count is down a little but well within safe range. Thanks james 2me
Permalink Reply by Xeljanzmiracle on October 28, 2016 at 4:02pm
My cholesterol has been high so my doctor lowered me back to 2 pills a day. I have drastically changed my diet so I can go back to 3 a day soon I hope.
Permalink Reply by mtran2000 on October 28, 2016 at 7:06pm
Xeljanz miracle I was under the impression you got results from 2 pills a day. Did you start on 3 a day?
Permalink Reply by Xeljanzmiracle on October 28, 2016 at 7:27pm
I started on 2, my hair grew back, but it started coming in faster, thicker, fuller and longer on 3. Just like Kyle Rhodes. I was also taking a LOT of BIOTIN. Walmart has the 10,000 mgs at really low prices. I need to stock up on that again.
Permalink Reply by DJ88 on October 29, 2016 at 5:55am

Hi XeljanzMiracle,

It's good to see your still making progress with Xeljanz. I was wondering how long have you been on Xeljanz before you decided to move up to 3 a day?

Permalink Reply by sadele on October 28, 2016 at 2:51pm
I got growth on my head and body, lashes came in but quickly fell out.
Right now I have almost a full head of hair but the front top is shedding a lot. It has thinned out so you can see my scalp.
Permalink Reply by Xeljanzmiracle on October 30, 2016 at 8:42am
Thanks DJ88. I started 3 a day around the 3 month period, which is what Dr. King did for Kyle Rhodes. I was fortunate, I had an overlap in shipping and started giving myself 3 a day before my next doctor's appointment. Then I told the doctor I was taking 3 and much to my surprise he refilled my prescription at that amount! I'm getting ready to go back k to 3 next week when my 3 month supply from the Hardship Program arrives.
Permalink Reply by Rascalx2 on October 31, 2016 at 2:34pm
Were you taking 3x a day (10mg,5mg,5mg) ?
Permalink Reply by Xeljanzmiracle on November 1, 2016 at 4:43am
5 mg three times a day
Permalink Reply by Rascalx2 on October 28, 2016 at 1:11pm
How were results for you? Im new on here, Im sure you have posted in past about growth. Ive been 11mg 1x a day for 3 1/2 months and have nothing yet.

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