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Xeljanz (Tofacitinib Citrate): My experience on the trial
I have received a lot of interest from others on here in my involvement with the Xeljanz trials at Yale.
I thought it would be nice for everyone if I documented my progress on here.
Xeljanz is a Jak3 inhibitor and is believed to work with alopecia by turning off the distress signal relayed by the hair follicle to the attacking immune system which is the cause of the hairs falling out. Xeljanz comes in a strength of 5mg per pill and a full box contains 60 tablets. The recommended dosage for arthritis is 1 tablet in the morning and another in the evening each day.
The trial is set in a series of stages and there are requirements before participating. These include monthly visits and blood tests every 2 weeks. Dr Brett King is absolutely fantastic and is an inspiration to me. His positivity and enthusiasm gives me the much needed hope I have craved for over a decade. I have been put on a low dose to start with which is 1 tablet every other day. My dosage has now been increased to 1 tablet every day and next month it could be increased to 2 tablets per day depending on the results.
I have completed my first month and have already noticed my alopecia has stabilised . I have not lost any existing hairs. In addition to this I have seen little hairs growing in my chest area as well as eyebrows. Fingers crossed! To date, I have experienced no side effects.
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AW: Other discussions on Xeljanz / Tofacitinib
https://alopeciaworld.com/main/search/search?q=Tofacitinib
Replies to This Discussion
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Permalink Reply by Nicolas on
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i tried to put a new discussion about the convention of yesterday in Torino of dot Brotzu...all cases of aa, also au resolved in traials whit his lotions...noone side effect ...cost approx 100 month ...and will be in commerce in 4-8 months like cosmetic so not need prescription ...but the discussion did not admit ...so i write here about this new lotion...the pictures he post in the convention are incredible, people whit au that have back all their hairs...and noon relapse...this is the solution and it's economic and noside effect...fidia will commerce it like cosmetic, so it's time to press Fidia to put in commerce soon this lotion...you can see the videos of the convention and the before and after pictures in this facebook group...https://www.facebook.com/groups/alopeciaeco/?hc_location=ufi
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Hi all, just giving an update...
I am a 26 year old female.
I am 26 weeks from the onset of my alopecia (became 100% AU within a month, hair loss was in diffuse pattern, no patches. No personal or family history of alopecia. No known trigger).
15 weeks on Xeljanz (6 weeks on 2 pills, 6 weeks on 3 pills, 2 weeks on 4 pills, 1 week on 3 pills.
Side effects: weight gain (15 lbs), exhaustion, 1 severe cold with fever that lasted 8 days.
Started seeing results 2 months in on Xeljanz.
Feeling good about my progress, but wish it was coming more quickly (obviously). No lashes or brows yet... - Attachments:
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IMG_1016.JPG, 2.6 MB
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Amazing growth Katrina ! So you haven't had alopecia long ? Looking forward to your future updates :)
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Permalink Reply by Xeljanzmiracle on
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Congratulations on your regrowth Katrina!
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Hello,
I am new to this forum. My 19 year-old daughter has had AU for 3 years. We had tried everything with no lasting results but she went on Xeljanz about 1.5 years ago. It took a while but in the last 6 months started seeing really good results and has her brows, lashes, body hair and short pixie now. Unfortunately, about 3 weeks ago she started shedding. Has this happened to anyone else? She feels like it is all falling out now. She takes 3 pills a day so don't know if we can go much higher. Was wondering if anyone had seen shedding after good results and if the shedding ever reversed? Thanks for anyone's advice!
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Permalink Reply by Suzie on
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I've only been on Xeljanz for a little over a month but i wasn't AU...just AA patches and thinning. From what I have learned about this disease is that it is so unpredictable and the Xeljanz is helping but is not a permanent fix. I also have RA and whatever medication I was on I would still have flare ups so nothing is full proof. Hopefully the shedding is her normal hair cycle and will continue to see growth. Hopefully she is still positive. Plus there are so many options out there for hair. I just traveled to FL to see Bobbi at Hair Therapy for Women. Look up her website...she is amazing!
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Thank you!
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Permalink Reply by Jcortez05 on
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I had full regrowth and then started shedding again but I think it's bc I had a really stressful event so I shaved it again in aug and have complete regrowth again ...
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Here is my hair after shaving it on AUg 17th ... (don't mind the snap chat filter I was just playing around with it )
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IMG_6608.JPG, 156 KB
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Thats good to hear. Did you lose most of your hair during the shedding or was it just in spots? I hate to tell her to shave it in case that makes it worse. Why do you think the shaving helped? Her Dr. wants her to take oral steroids in conjuction with the Xeljanz for a short period to hopefully stop the fallout and maybe that will help. What dose of Xeljanz are you on? Thanks for sharing!
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