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Xeljanz (Tofacitinib Citrate): My experience on the trial
I have received a lot of interest from others on here in my involvement with the Xeljanz trials at Yale.
I thought it would be nice for everyone if I documented my progress on here.
Xeljanz is a Jak3 inhibitor and is believed to work with alopecia by turning off the distress signal relayed by the hair follicle to the attacking immune system which is the cause of the hairs falling out. Xeljanz comes in a strength of 5mg per pill and a full box contains 60 tablets. The recommended dosage for arthritis is 1 tablet in the morning and another in the evening each day.
The trial is set in a series of stages and there are requirements before participating. These include monthly visits and blood tests every 2 weeks. Dr Brett King is absolutely fantastic and is an inspiration to me. His positivity and enthusiasm gives me the much needed hope I have craved for over a decade. I have been put on a low dose to start with which is 1 tablet every other day. My dosage has now been increased to 1 tablet every day and next month it could be increased to 2 tablets per day depending on the results.
I have completed my first month and have already noticed my alopecia has stabilised . I have not lost any existing hairs. In addition to this I have seen little hairs growing in my chest area as well as eyebrows. Fingers crossed! To date, I have experienced no side effects.
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AW: Other discussions on Xeljanz / Tofacitinib
https://alopeciaworld.com/main/search/search?q=Tofacitinib
Replies to This Discussion
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Permalink Reply by Jane on
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Hello
My Dr. just told me about tofacitinib. He said it is coming to the market this year. It sounds like some of you are on it. How can I get information if it is available yet.
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Reporting on my son's progress after being on Xeljanz for 2 months.
AA began August 2016 and rapidly progressed to AU with total baldness, total loss of arm and leg hair with patchy loss of eyebrows and eyelashes.
Today he has about an inch or more of hair in blotches on about 50% of his head! Not fuzz, but fine hair.
And to Xeljanz non-responders, I have good news for you, too:
Northwestern University in Chicago is doing research on a different drug for alopecia.
Pro is that the drug is then free, the negative is that it's a double-blind study so that means half get the drug and half get the placebo.
Good luck, all!
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It really is. I never see his head so it was a complete surprise when he took his hat off. He starts college in August so I am praying he has a full head of hair by then.
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I should have asked. I am so disappointed that I didn't. But truthfully, I was thinking this whole time that the research was on Xeljanz,and that my son would be be enrolled in the study and we'd get it for free since we're getting nowhere in regard to insurance coverage.
What I think is very positive, though, is that it is NOT Xeljanz so all of the people on this thread who are non-responders have hope.From what the Dr said, I am under the impression that other manufacturers are seeing a need for this and are already jumping into the market meaning affordable and effective medicine for us all.
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Do xeljanz cut after completion of treatment, hair loss has been observed?
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is it baraticinib?
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I am sorry I didn't ask.
I regret it.
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anybody tried dog med apoqual for AA ..its jak inhebitor
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Permalink Reply by macdev on
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Apoquel (oclacitinib) est un JAK inhibiteur spécifique JAK1 , utilisé dans les dermatites allergiques du chien...Je ne sais pas si il a été testé chez l homme ..Chez le chien , il est utilisé à la dose de 04.à 0.6 mg/ kg.. Il est très possible qu'à une dose supérieure , il soit inhibiteur de JAK 1 .2....
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