Alopecia World
www.alopeciaworld.com
Xeljanz (Tofacitinib Citrate): My experience on the trial
I have received a lot of interest from others on here in my involvement with the Xeljanz trials at Yale.
I thought it would be nice for everyone if I documented my progress on here.
Xeljanz is a Jak3 inhibitor and is believed to work with alopecia by turning off the distress signal relayed by the hair follicle to the attacking immune system which is the cause of the hairs falling out. Xeljanz comes in a strength of 5mg per pill and a full box contains 60 tablets. The recommended dosage for arthritis is 1 tablet in the morning and another in the evening each day.
The trial is set in a series of stages and there are requirements before participating. These include monthly visits and blood tests every 2 weeks. Dr Brett King is absolutely fantastic and is an inspiration to me. His positivity and enthusiasm gives me the much needed hope I have craved for over a decade. I have been put on a low dose to start with which is 1 tablet every other day. My dosage has now been increased to 1 tablet every day and next month it could be increased to 2 tablets per day depending on the results.
I have completed my first month and have already noticed my alopecia has stabilised . I have not lost any existing hairs. In addition to this I have seen little hairs growing in my chest area as well as eyebrows. Fingers crossed! To date, I have experienced no side effects.
-----------------------------
AW: Other discussions on Xeljanz / Tofacitinib
https://alopeciaworld.com/main/search/search?q=Tofacitinib
Replies to This Discussion
-
Permalink Reply by Jcortez05 on
-
Don’t think like that ! I saw dr bordane at Columbia University but she didn’t take my insurance at the time so I couldn’t see her again but she is so nice and she will help u !! Where do u live ?
-
Permalink Reply by Sad_Rapunzel on
-
Thank you for your reply
I'm visiting my family in Ukraine now, and will be back in New York in the end of March...
How did she help you? Were you prescribed with Tofacitinib?
-
-
She was going to prescribe xeljanz but I had to get blood work first at her office but she didn’t accept my insurance so I couldn’t , I just found a rheumatologist in my town that accepted my insurance and he’s who I currently see .. also a member here by the name Katie girl sees her too and she is on xeljanz
-
-
Also , have you had blood work done? You may have thyroid issues and that’s causing your hair loss in which a diff medication may work for you
-
Permalink Reply by AnakinWildstar69 on
-
Hi. ALWAYS CHOOSE LIFE. Suicide is for the weak-minded. I've had AU for 16 years, and I've survived it without one tear shed. I even got microblading along with micropigmentation on my scalp and it looks great. I rarely wear hats/beanies anymore, beacuse my 'new hair' looks better than before my AU took it all away. Then again, your'e female, you probably don't like the 'shaved/bald-hair' look. I even got mustache pigmentation, which looks 100% natural/normal. So, there IS ONE WAY TO GET YOUR HAIR BACK. I suggest you watch the youtube video "John Bergman-autoimmunity-2018"...and he NAILS it for us all..i.e, he shows you how/why you lost your hair due to an AUTOIMMUNE dis'ORDER'..your immune system's working perfectly, it's just pointed in the wrong direction. He shows you how to reset your immune system's memory by fasting for 3-4 days straight, as well as simple Eating/Exercising/StressManagement/Sleep..as well as removing/reducing garbage grocery store foods that make us sick and make us have these autoimmune responses. We're lucky actually. We have the only autoimmune disorder that brings no physical pain. REVERSE OUR AUTOIMMUNITY...it's not impossible....follow that youtube video i posted, and watch what happens =D i'm starting it on April 1st....your turn =D
-
-
I'd rather have some disease with lethal ending, then this.
I feel ugly all the time. An, I could not pull off bald chick hair style. I was famous for my long thick hair, so now I can't even meet with my old friends or relatives - I'm too ashamed of my look. I'm too suicidal every day. And I'm telling you, If I'd have a Cyanide pill in front of me I'd not think a second -I'd take it right away.
-
Permalink Reply by Kathy on
-
Rapuzel, I'm not sure where you live but someone can recommend a quality wig place. The good ones are very kind and supportive and will not let you walk out the door unless you look wonderful. After years of suffering I got my "hair topper"and it made a huge difference. You buy only real hair and they aren't cheap but worth every penny. I wore it everyday while I continued searching and it calmed my psychie down tremendously.
I have also heard a lot of talk about Rogaine. My dr had me on that for years, then a friend told me about DR Yaker in Dallas. He has a proprietary formula and she had great success. I did a Skype appointment with him and he explained it was for female pattern baldness and would obviously not cure alopecia but its gentler and more effective than Rogaine. I'm starting my second year and my scalp feels better and it works better than Rogaine.
-
-
Oh no.. Not Rogaine....
This is so sad I can't even tell you how awful this is to read.
-
-
Pretty bold.. he's an amazing doctor outside of alopecia, he's been on TV for vitiligo and his amazing research in that department.
Let's not get it twisted, this is a form of therapy that works and he's leading the for front as well as the great researchers at Columbia .
-
-
I understand, I just want to be sure.
You see, in Ukraine and Russia they don't even know about this medicine. We have forum like this and it's full of people who's been stuggling for decades, and all they have is Minoxidil. They keep telling me I have no other hope and I have already lost a lot of time not starting to use it, which I don't want to do, because... well... it's for a lifetime! and it's still not researched enough to be sure you'll not mutate to X-men in 10-15 years of using. and you can predict where your hair will or will not grow: you can still be bald, but will have beard like Pushkin, and be a girl at the same time
-
-
Sad rapunzel,
it is very hard at the beginning of this condition particularly. There are definitely more options then minoxidil. And if you still have 50% of your hair there is a good chance you will regrow in time. That said, options that are pretty affordable everywhere include; cyclosporine treatment, oral steriod pulsing, methotrexate, topical steriods, steriod injections, laser therapy and topical irritants. All these have health consequences and you need to familiarise yourself with the side effects and whether these options would be ok for your personal health situation. There are affordable options regarding Jak inhibitors too, though what affordable to me, may not be affordable to you as I understand cost of living, income etc varies vastly amongst countries, as do the ability to import medications legally. Regardless let me tell that we all felt your pain, deeply, and the beginning is by far the worst, but there are options, don’t let anyone tell you that minoxidil is all there is. Some people come to a peace with alopecia and do not feel that treatment is for them which is absolutely cool, others seek out every option out there to find something. More and more treatments will be available and affordable in the near future. Please hold on to that. Alopecia is not hopeless - it just a matter of getting your head around the options, figuring out what’s for you and developing a plan.-
-
-
I have never herard about these options.
Steroids are way to harmful. Most scary thing of all these hormonal/steroids injections/pills for me personally is unpredictable reaction of body weight. I know cases when women just suddenly become a bubble and no diet could help, just being on hormones-steroids gave that result.
But thank you a lot.
If anybody here has Dr.King's email please dm me, I want write to him to see if he even my specialists, or he will just transfer me to another doctor.
I am ready to pay any money now.
Also, Somebody here mentioned that start Xeljanz himself. Where could I buy original version?
© 2024 Created by Alopecia World.
Powered by
