Knowledge about SARS-CoV-2 vaccine safety and benefits is evolving to support decision-making about use of these vaccines. Although benefits of these vaccines greatly overweight risks associated with acquisition of infection, the benefit-risk balance should be communicated to patients. There is currently a lack of clear-cut recommendations about screening for autoimmunity in patients receiving SARS-CoV-2 vaccines and autoimmunity in this context is multifactorial with multiple modifiers. Due to the growing reports of autoimmunity flares including AA, healthcare providers should remember to enquire about personal and/or family history of autoimmunity. This would allow for proper patient-centered counselling and enable patients to take informed health decisions in their best interest.
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Alopecia Areata Universalis Precipitated by SARS-CoV-2 Vaccine
"Knowledge about SARS-CoV-2 vaccine safety and benefits is evolving to support decision-making about use of these vaccines. Although benefits of these vaccines greatly overweight risks associated with acquisition of infection, the benefit-risk balance should be communicated to patients."
A Case Report and Narrative Review
Introduction:
Hair loss is a common presentation in primary care. Among various causes of hair loss, alopecia areata (AA) represents 18.2% of the causes [1] and has a lifetime risk of approximately 2% [2,3]. AA is a patchy nonscarring alopecia with underlying autoimmunity against hair follicles with resultant dystrophy of the hair follicle at the anagen phase of growth [3,4]. Severe forms of AA include alopecia totalis (all scalp hair) and universalis (entire body). Despite multiple underlying pathophysiological mechanisms, there are two well-established primary explanations. The immune dysregulation with loss of immune privilege of hair follicles and genetic predisposition [3,5]. Other factors include infections, drugs, and vaccines with consequent immune dysregulation and development of AA.
Wise, Kiminyo, and Salive's 1997 study was among the earliest reports of hair loss after routine immunizations in their case series [6]. It is suggested that vaccines via antigen presentation, cytokine production, epitope spreading, polyclonal activation of B cells, and other mechanisms of anti-infectious immune response and autoreactivity potentially trigger autoimmunity [7]. Regarding severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines, there is a theoretical risk of inducing autoimmunity and a number of reports of different autoimmune sequela [8]; however, most frequently used messenger ribonucleic acid (mRNA) vaccines have excluded patients with a history of autoimmune conditions from their clinical trials. The US Food and Drug Administration has raised the concern of possible precipitation of rheumatoid arthritis after SARS-CoV-2 vaccination [9]. Pfizer vaccine developers have included a list of rare complications, including myocarditis and skin reactions, in the information leaflet, but AA was not listed.
In addition to the morbidity burden of AA, it is distressing to affected patients and is associated with major psychosocial sequelae and reduced quality of life [10]. This report presents a patient with alopecia universalis recurrence precipitated by the SARS-CoV-2 vaccine.
Conclusions:
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Comment by Kathy on September 12, 2022 at 10:06am
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This article confirms my theory that every time I get a vaccine my AA kicks up and I lose at least 50% of my hair. I kept my AA records for the last 15 years, every time I had a surge in hair loss and when I was more stable. Every supplement I tried etc. It finally became clear to me that vaccines were my main trigger. Nice to know its been studied, Dr's would never address this when I would bring it up.
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It's not exactly accurate to say that vaccines are supposed to contain an attenuated virus. First, not all vaccines are for viral infections. There are vaccines for bacterial infections, as well. Second, not all pathogens are attenuated. Attenuated refers to receiving a live, weakened organism in your vaccine. Live organisms can sometimes be risky for people with weakened immune systems. Vaccines can also be made with inactivated organisms (killed). These are not capable of causing disease, but also may not provide the strongest immune response. mRNA vaccines work by teaching your body how to make its own copies of the spike protein which your body then recognizes and produces an immune response to. Viruses work by invading your body, taking over your protein manufacturing process and turning you into a virus duplication factory. Those infectious, duplicated viruses then spread to other people you encounter. mRNA vaccines mimic COVID infection without teaching you to produce the whole virus, just the noninfectious spike protein. mRNA is a natural part of how your body sends protein making messages. The mRNA vaccine is basically an external message. Other vaccines like recombinant, subunit, conjugate, etc use a unique piece of an organism instead of a whole inactivated or attenuated organism. Since it is just small piece (variety of production methods depending on organism/manufacturer), it is not capable of inducing infection. It does, however, usually elicit a strong immune response.
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Following my Pfizer covid vaccination-2 shots my hair loss escalated. I now have Alopecia Universalis with absolutely zero hair on my body. The hair on my head came off like I had used Nair hair removal following the Covid vaccination. I have struggled with Alopecia for decades and I now have zero hair and zero hope that my hair will ever return. I am wondering if there's been an increase in Alopecia cases post global Covid vaccinations? Anyone know of any studies or stats on that?
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Comment by Matt1 on November 16, 2022 at 6:21am
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Read the Pfizer papers, there’s nothing good in this experimental “vaccine” in fact if you look at side affects of vaccines given to you in your childhood you may notice one that is always on the list. I’m sorry Cheryl but you are very much incorrect on saying there’s any safety in the vaccine you referred to. I really don’t know how people can completely disregard the Pfizer papers and now the studies done in the UK and Jerusalem and the rising death rates around the world of young people/healthy people, miscarriages have skyrocketed by 100’s of percent since the use of this vaccine has started. The lists go on and on, stop trusting main stream media sources and the tv doctors. The information is available if you need me to forward you supporting documents of what I stated I am willing to do so. But the best place to start is the Pfizer papers.
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Comment by dreamscometrue on November 19, 2022 at 10:59pm
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I totally agree with you on this @Matt1, especially after Pfizer was forced by court of law to disclose whats exactly in those vaccines despite asking the court to seal that information for the next 75 years. What is in those vaccines that would make a large company like that want to keep sealed the contents? And better yet, why would people even trust a company like that and offer up you body for them, just because they claim it prevents a virus from infecting you, which we now know thats not true at all? Imo, I think those vaccines are questionable at the very least, and highly suspect at best. I pray for those who are vaccinated because the long term affects are still unknown, and they ONLY decided to do studies on WHY people are experiencing myocarditis, SADS, autoimmune disease, peri-carditis, Bells Palsy among other diseases. Its sad and awful the stories I've seen and heard.
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