Xeljanz (Tofacitinib Citrate): My experience on the trial

I have received a lot of interest from others on here in my involvement with the Xeljanz trials at Yale.

I thought it would be nice for everyone if I documented my progress on here. 

Xeljanz is a Jak3 inhibitor and is believed to work with alopecia by turning off the distress signal relayed by the hair follicle to the attacking immune system which is the cause of the hairs falling out. Xeljanz comes in a strength of 5mg per pill and a full box contains 60 tablets. The recommended dosage for arthritis is 1 tablet in the morning and another in the evening each day.

The trial is set in a series of stages and there are requirements before participating. These include monthly visits and blood tests every 2 weeks. Dr Brett King is absolutely fantastic and is an inspiration to me. His positivity and enthusiasm gives me the much needed hope I have craved for over a decade. I have been put on a low dose to start with which is 1 tablet every other day. My dosage has now been increased to 1 tablet every day and next month it could be increased to 2 tablets per day depending on the results. 

I have completed my first month and have already noticed my alopecia has stabilised . I have not lost any existing hairs. In addition to this I have seen little hairs growing in my chest area as well as eyebrows. Fingers crossed! To date, I have experienced no side effects.

-----------------------------

AW:  Other discussions on Xeljanz / Tofacitinib

https://alopeciaworld.com/main/search/search?q=Tofacitinib

 

Views: 927908

▶ Reply to This

Replies to This Discussion

Permalink Reply by Starshine on October 23, 2015 at 10:01am
Hi Football Fan. My insurance pays half and Phizer hardship pays the remainder. Since it is split, they never questioned it. My doc called it in to my spacialty pharmacy, not theirs, and they paid, no problem. In Your case, I would call, or have your doc call Zelsource and tell them you need to take three pills a day and ask if they will cover it. I was assigned a case manager for questions or concerns.
Permalink Reply by singh on October 21, 2015 at 1:44am
Can anyone reccommend what times to have the xeljanz? Or how many hours between? I read that it has a half life of 3 hours not sure if that makes a difference in the gap you have them apart ? Thanks
Permalink Reply by Xeljanzmiracle on October 21, 2015 at 9:00am
I don't have any set times. I just take one in the morning and one at night, when I remember to. Don't worry Singh and try not to analyze too much. You finally got the drug, take it and have faith that it will work. What is your background? Are you AU?
Permalink Reply by singh on October 21, 2015 at 11:21am
Thank you and yes I will have do and I am now AU for the last 8 months I have had AA then AT for some years now. Am
Still looking forward to the data getting released from Dr King and others. I really hope they give us more hope
Permalink Reply by DJ88 on October 23, 2015 at 7:21am

Hey guys,

I was wondering, What happened to that October clinical trial? Did they release the results yet?

Permalink Reply by singh on October 24, 2015 at 10:39am
http://www.nbcnews.com/health/health-news/cancer-drug-could-be-bald...

What you think of this ? Are we closer to a cure?? Just seen this online today
Permalink Reply by Xeljanzmiracle on October 24, 2015 at 11:18am
Wow! That's exciting! Not only for us, but for those with male pattern baldness, which affects the majority of bald men.
Permalink Reply by singh on October 24, 2015 at 11:30am
Yeh it is I seen that this morning ! It will be a safer profile too but would be annoying to rub it all over your head all the time but still it's good :). She also mentioned she has finished her trials for the other jak inhibitor and that and xeljanz is definitely the treatment for alopecia so far !.
Permalink Reply by Sp06 on October 24, 2015 at 1:22pm
http://m.medicalxpress.com/news/2015-10-blocking-enzymes-hair-folli...
This site has a video of dr christiano talking abt the findings, i found it interesting.

How long do u guys think it would take before something like this would become available for use by everyday patients? I have a feeling it might not be too soon, but i rly hope it is. Right now taking xeljanz orally is probably the best and only option.
Permalink Reply by singh on October 24, 2015 at 2:46pm
Interesting video. I think personally now within 2 years at first I thought about 4 years so by 2020 but I feel it's pushing in the right direction that now I feel hopefully stem cell treatment will be here soon as a cure! I know trials have been successful in that too. Also baricitinib will get approved early 2016 it's cheaper and safer hopefully so people can switch to that while waiting for the topical version and a cure.
Permalink Reply by Football fan on October 24, 2015 at 2:52pm
That's for all this positive news!!!!
Permalink Reply by singh on October 24, 2015 at 4:04pm
Your welcome mate hope yours is improving too :)

RSS

Disclaimer

Any mention of products and services on Alopecia World is for informational purposes only; it does not imply a recommendation or endorsement by Alopecia World. Nor should any statement or representation on this site be construed as professional, medical or expert advice, or as pre-screened or endorsed by Alopecia World. Alopecia World is not responsible or liable for any of the views, opinions or conduct, online or offline, of any user or member of Alopecia World.

© 2024   Created by Alopecia World.   Powered by

Badges  |  Report an Issue  |  Terms of Service