Xeljanz (Tofacitinib Citrate): My experience on the trial

I have received a lot of interest from others on here in my involvement with the Xeljanz trials at Yale.

I thought it would be nice for everyone if I documented my progress on here. 

Xeljanz is a Jak3 inhibitor and is believed to work with alopecia by turning off the distress signal relayed by the hair follicle to the attacking immune system which is the cause of the hairs falling out. Xeljanz comes in a strength of 5mg per pill and a full box contains 60 tablets. The recommended dosage for arthritis is 1 tablet in the morning and another in the evening each day.

The trial is set in a series of stages and there are requirements before participating. These include monthly visits and blood tests every 2 weeks. Dr Brett King is absolutely fantastic and is an inspiration to me. His positivity and enthusiasm gives me the much needed hope I have craved for over a decade. I have been put on a low dose to start with which is 1 tablet every other day. My dosage has now been increased to 1 tablet every day and next month it could be increased to 2 tablets per day depending on the results. 

I have completed my first month and have already noticed my alopecia has stabilised . I have not lost any existing hairs. In addition to this I have seen little hairs growing in my chest area as well as eyebrows. Fingers crossed! To date, I have experienced no side effects.

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AW:  Other discussions on Xeljanz / Tofacitinib

https://alopeciaworld.com/main/search/search?q=Tofacitinib

 

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Permalink Reply by Joserid on May 25, 2021 at 6:14pm

Hi Cassidymain,

How was your case? AU, AA? How long ago?

The study has been based in Xeljanz? What dosage?

Congrats!

Permalink Reply by Cassidymain on May 27, 2021 at 1:23pm

i’m in the pf-06651600 trial and i was AU! i’ve been on the trial for two and a half years now and was AU for three years before that but AA for two years before that, Now i’m on 50 mg of drug and i don’t know how that would translate to xeljanz or how to figure that out.

Permalink Reply by kevin on May 26, 2021 at 5:07pm

hi you can get it in Bangladesh it is a generic box of 11mg is 30 dollars there are several posts on this subject it is legitimate i had it tested in the laboratory. afterwards I do not know how it goes with your customs but look at the posts on this subject.

Permalink Reply by Lori on July 28, 2021 at 1:00am

Hi Kevin Can you send me the site information.  I was on the assistance program for three years hair grew back but have lost it again and they refused my assistance program since COVID started I need to find a company to order from.losing all my hair growth.

Permalink Reply by kevin on May 26, 2021 at 5:13pm

if you need i would give you the email from my usual supplier you ask him for the number of boxes you want tofacinix 11mg and he will invoice you i pay them with transferwise it is the easiest and fastest the pharmaceutical company is pharmaceutical tag there are several posts on this subject. they do baracitinib and generic xeljanz it depends which jak inhibitor are you using in your clinical trial

Permalink Reply by Cassidymain on May 27, 2021 at 1:25pm

That would be so helpful thank you!  I’m in the pf-06651600 which inhibits jak3. 

Permalink Reply by kevin on May 27, 2021 at 5:51pm

I added you as a friend

Permalink Reply by Patricia on May 30, 2021 at 3:31am

I have been using xeljanz for 4 years   I buy from Beacon in india..

Go to their site and click on fast delivery on the top right hand of their page.

All the information is there. Dont be afraid! They are a reputable company.

Permalink Reply by valevan85 on May 28, 2021 at 5:07pm

how many tablets of tonifacinix do you assume?what other medicine do you do with tonifacnix???i am on tonifacinix 16 mg 11 morning and 5 mg at the night but the air not develompent ,,i am whith universalis ....what advice do you do for me?

Permalink Reply by kevin on May 28, 2021 at 8:55pm

you have been using this for more than 6 months and no response

you can try baracitinib 4mg

Permalink Reply by mastros on May 29, 2021 at 3:12am

Hello all,

I have been doing really well in terms of hair. My bloodwork has been also all ok. I have been tapering my dose since December 2020. Instead of taking 20mg/day for the whole week, I am taking 15mg/day for two days and 20mg/day the rest. I was supposed to be on 15mg/day 3 days per week. I tried it a couple of times, had some minor tiny spots and retracted back to 2 days per week 15mg/day. 

I have also been taking Minoxidil 10mg/day constantly since late 2019. My view is that it helped to close the minor spots. 

You can see in the attachment my progress over the years. 

Attachments:
Permalink Reply by Keithm15 on August 31, 2021 at 9:25pm

Any issues with taking Minoxidil? My dr recommended taking it with xeljanz, but the side effects list had me slightly worried. 

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