Xeljanz (Tofacitinib Citrate): My experience on the trial

I have received a lot of interest from others on here in my involvement with the Xeljanz trials at Yale.

I thought it would be nice for everyone if I documented my progress on here. 

Xeljanz is a Jak3 inhibitor and is believed to work with alopecia by turning off the distress signal relayed by the hair follicle to the attacking immune system which is the cause of the hairs falling out. Xeljanz comes in a strength of 5mg per pill and a full box contains 60 tablets. The recommended dosage for arthritis is 1 tablet in the morning and another in the evening each day.

The trial is set in a series of stages and there are requirements before participating. These include monthly visits and blood tests every 2 weeks. Dr Brett King is absolutely fantastic and is an inspiration to me. His positivity and enthusiasm gives me the much needed hope I have craved for over a decade. I have been put on a low dose to start with which is 1 tablet every other day. My dosage has now been increased to 1 tablet every day and next month it could be increased to 2 tablets per day depending on the results. 

I have completed my first month and have already noticed my alopecia has stabilised . I have not lost any existing hairs. In addition to this I have seen little hairs growing in my chest area as well as eyebrows. Fingers crossed! To date, I have experienced no side effects.

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AW:  Other discussions on Xeljanz / Tofacitinib

https://alopeciaworld.com/main/search/search?q=Tofacitinib

 

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Permalink Reply by AlopeciaDestroyedMyLife on November 7, 2015 at 3:04pm

That's fantastic Xeljanzmiracle, 

It's pretty even actually on both sides ,

Some parts fill in more than others but it would be the same for the other side too. 

Permalink Reply by 3ebdie on November 7, 2015 at 5:34pm

Hey man

I did send you a message. Could you please tell us which Turkish pharmacy you exactly went for the Xeljanz? As you have verified with Pfizer they are legit I would like to go to the same location. Thanks!!

Permalink Reply by Juan on November 8, 2015 at 11:02pm

Hi Mate,

I have had AU since 2012. I am 26 yrs old and I've been told about Xeljanz. 

I would love to have the hair back at least eyelashes and eyebrows, but I have many questions about the treatment

First of all, tell me about side effects you experienced? How old are you?

Permalink Reply by Carol on November 9, 2015 at 8:19am
Hi ADML, very happy for you! What dose are you on right now, and what do you think about a maintenance dose?
Permalink Reply by AlopeciaDestroyedMyLife on November 11, 2015 at 8:22am

Hi, 

Right now I am back on 2 pills a day . As for maintenance it would be different from person to person but 1 pill every 2-3 days would be a logical start . 

Permalink Reply by Xeljanzmiracle on November 9, 2015 at 9:41am
Thank you ADML. It's good to hear from you directly. I have been hoping/waiting to hear from you since I started posting on this site in July. This disease has its disadvantages, but connecting to others and sharing our support and encouragement with one another is a DAILY BLESSING that has really enriched my life!
Permalink Reply by AlopeciaDestroyedMyLife on November 11, 2015 at 8:23am

I'm so glad , how is your regrowth coming along?

Permalink Reply by Xeljanzmiracle on November 12, 2015 at 2:51am
It's great! Without sounding redundant, I have dark pigmented hair on my scalp, both eyebrows coming in, and left eyelashes trying to emerge from under left lid. Saw first eyelash on right side last week.Thanks for asking. I'm glad your depression is lifting. You seem to be more interactive with the folks on YOUR BLOG, lol! Which is the most popular and useful one on here.
Permalink Reply by Peachfuzz on November 9, 2015 at 4:20am

Thats amazing and insipring info ADML, do you worry at all about longer term side affects? What are the chances of the new drugs being harmful?

Permalink Reply by AlopeciaDestroyedMyLife on November 11, 2015 at 8:25am

Thanks Peach,

It does cross my mind from time to time but taking into account the progress I've made so far I couldn't stop taking it. 

With Xeljanz there is a good chance you would get an upper repository tract infection which is fairly common. There is also a small chance of something more serious .

Permalink Reply by Kasten on November 9, 2015 at 4:38pm

Congrats!!! I'm looking forward to seeing your pics.  

Permalink Reply by Sabri on November 8, 2015 at 11:01am

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