I have received a lot of interest from others on here in my involvement with the Xeljanz trials at Yale.

I thought it would be nice for everyone if I documented my progress on here. 

Xeljanz is a Jak3 inhibitor and is believed to work with alopecia by turning off the distress signal relayed by the hair follicle to the attacking immune system which is the cause of the hairs falling out. Xeljanz comes in a strength of 5mg per pill and a full box contains 60 tablets. The recommended dosage for arthritis is 1 tablet in the morning and another in the evening each day.

The trial is set in a series of stages and there are requirements before participating. These include monthly visits and blood tests every 2 weeks. Dr Brett King is absolutely fantastic and is an inspiration to me. His positivity and enthusiasm gives me the much needed hope I have craved for over a decade. I have been put on a low dose to start with which is 1 tablet every other day. My dosage has now been increased to 1 tablet every day and next month it could be increased to 2 tablets per day depending on the results. 

I have completed my first month and have already noticed my alopecia has stabilised . I have not lost any existing hairs. In addition to this I have seen little hairs growing in my chest area as well as eyebrows. Fingers crossed! To date, I have experienced no side effects.

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AW:  Other discussions on Xeljanz / Tofacitinib

https://alopeciaworld.com/main/search/search?q=Tofacitinib

 

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Hi Xeljanzmiracle
Hopefully cure for AU will come soon ,for all patients even kids .
Maybe stemcell therapy will be the cure ...
But still long way to be approved by FDA .
Sara, Yes, there will be a permanent cure for ALL diseases and ailments, even death. Private message me if you are interested and I will share that good news with you.
Hi Xeljanzmiracle
I have sent the message

i think even mesotherapy may help boost hair growth  caused by jak inhibitors

mesotherapy should  be  cheap...i will try it if i can in future ..i am having very tiny hair growth but i feel my head has became unfertile lol..hair growth has been always slow since i have became alopecia totalis

just sharing my thoughts . 

 

Aladin can you help me...my xelijanz will mdure only other 6 weeks and i'm afraid it will be no sufficient

 have other questions sorry :

how i can calculate 10 mc every day..and i must take them in a pill or in another way? 

how have you made?

can you help?

the site where are factories that sell baricitinib is amazon or alibaba?

i read this study made whit a lot of people(1000) ony one let the cure and in palcebo half also one let the cure so this drougs HAS NOT SIDES EFFECT ...

Also in this study they give to people 1 time a day cuase the drougs is not like xelijanz that work 12 hours it work 24 hours so better you take it a time a day no 2 times

it's in italian but sure a lot of other trials made in Usa or other countries 

http://www.lilly.it/it/area-stampa/articoli/baricitinib-un-innovati...

Aladin and other supplieres what do you think baricitinib topical cream ???

This is one I plan on switching to as soon as possible...once it hits the market. A better safety profile and should bring the price down of both drugs; xeljanz will no longer be the only player in this space.

baricitinib appears promising on paper however we must take on board that baricitinib has no visible testing profile except the one example of the of a young chap who had his AA reversed. It is very attainable on aliexpress and alibaba.com china for reasonable prices ($300-$400 per gram) and would be great if we had more users to supply their experiences if there is any on this forum. It would be a nice alternative to xeljanz for those who cannot receive xeljanz in their countries . 

How many pills a month can that eqaite too ?

1 gr(to me made 520 doll) work for 3 months...so very economic, the question is: like make it in pills? or again better like make it in topical cream? is there anyone can help us? 

I'm full AU. I've been on Ruxolitinib + prednisone for 5 months, had been on Xeljanz for 6 months prior with no results. So far on Ruxolitinib and prednisone facial fair, 60 % + of eyebrows and eyelashes, and all nose hair have returned. Scalp is covered in patches of dark terminal hair that continues to spread to fill in. I was shaving my head every 2 weeks, up to every 3rd day. Oddly no other body hair or pubic hair?

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