Alopecia World
www.alopeciaworld.com
Xeljanz (Tofacitinib Citrate): My experience on the trial
I have received a lot of interest from others on here in my involvement with the Xeljanz trials at Yale.
I thought it would be nice for everyone if I documented my progress on here.
Xeljanz is a Jak3 inhibitor and is believed to work with alopecia by turning off the distress signal relayed by the hair follicle to the attacking immune system which is the cause of the hairs falling out. Xeljanz comes in a strength of 5mg per pill and a full box contains 60 tablets. The recommended dosage for arthritis is 1 tablet in the morning and another in the evening each day.
The trial is set in a series of stages and there are requirements before participating. These include monthly visits and blood tests every 2 weeks. Dr Brett King is absolutely fantastic and is an inspiration to me. His positivity and enthusiasm gives me the much needed hope I have craved for over a decade. I have been put on a low dose to start with which is 1 tablet every other day. My dosage has now been increased to 1 tablet every day and next month it could be increased to 2 tablets per day depending on the results.
I have completed my first month and have already noticed my alopecia has stabilised . I have not lost any existing hairs. In addition to this I have seen little hairs growing in my chest area as well as eyebrows. Fingers crossed! To date, I have experienced no side effects.
-----------------------------
AW: Other discussions on Xeljanz / Tofacitinib
https://alopeciaworld.com/main/search/search?q=Tofacitinib
Replies to This Discussion
-
Permalink Reply by Rascalx2 on
-
So ive been getting lightheaded, feel weak, and lack of endurance for exercise.. i used to be able to push through the day, workout, task.. etc., but lately am just empty w none left in tank, been on xeljanz for 2 years and was on 20 mg , went diwn to 15 mg and starting to have some shedding.. so tired of this, i dont want to lose all my hair and back to au, but feel some side effects for sure.. anyone else having similar issues? I get so pissed that I have this f**ckng auto immune disease, !! And whats more frustrating is noone knows shit about it.. its unpredictable is the only sure thing anyone kniws.
-
Permalink Reply by Carlie on
-
I've been taking Xeljanz now for about 6 weeks and lately I've been having severe night sweating. I hardly sweat in the heat of the summer so sweating is unusual for me. Anyone else experience this side effect?
-
-
Anyone here taken 30 mgs Xeljanz a day or higher after seeing no results on lower dosages? How high did you go? DId it produce results?
I am 14.5 weeks into Xeljanz, no results at all (I am AU), and am 30 mgs/day.
Thanks!
-
-
Seems like a crazy high dosage! Some people took only a month on 10mg to see results others took 6 months.I never saw results on 10,15,or 20mg not willing to go higher waiting for something new to get approved with a different pathway.You definitely need more time before you know if your a responder or not,
-
-
My doc will put me up to 60 if after two months at 30 I still get nothing. Thanks for letting me know that it can take up to 6 months tho. I figure I will go up higher as long as my doc is willing and as long as all my blood tests, BP, etc remain healthy.
-
-
Anna, just messaged you. I've been Au since November of 2016. I have been taking xeljanz for 7 weeks and getting 1 Kenalog injection every 11 weeks. I'm seeing quite a bit of growth, including eyelashes and eyebrows. I didn't see much until I started the injections. Hoping it holds and my insurance will kick in.
© 2024 Created by Alopecia World.
Powered by
