Xeljanz (Tofacitinib Citrate): My experience on the trial

I have received a lot of interest from others on here in my involvement with the Xeljanz trials at Yale.

I thought it would be nice for everyone if I documented my progress on here. 

Xeljanz is a Jak3 inhibitor and is believed to work with alopecia by turning off the distress signal relayed by the hair follicle to the attacking immune system which is the cause of the hairs falling out. Xeljanz comes in a strength of 5mg per pill and a full box contains 60 tablets. The recommended dosage for arthritis is 1 tablet in the morning and another in the evening each day.

The trial is set in a series of stages and there are requirements before participating. These include monthly visits and blood tests every 2 weeks. Dr Brett King is absolutely fantastic and is an inspiration to me. His positivity and enthusiasm gives me the much needed hope I have craved for over a decade. I have been put on a low dose to start with which is 1 tablet every other day. My dosage has now been increased to 1 tablet every day and next month it could be increased to 2 tablets per day depending on the results. 

I have completed my first month and have already noticed my alopecia has stabilised . I have not lost any existing hairs. In addition to this I have seen little hairs growing in my chest area as well as eyebrows. Fingers crossed! To date, I have experienced no side effects.

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AW:  Other discussions on Xeljanz / Tofacitinib

https://alopeciaworld.com/main/search/search?q=Tofacitinib

 

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Replies to This Discussion

Permalink Reply by singh on December 31, 2016 at 6:48pm
What is the dose your daughter is on plz ?
Permalink Reply by Alo-mom on January 4, 2017 at 12:21pm

She is taking one pill in the morning 5 milligrams and 2 5 milligrams at night.

Permalink Reply by singh on January 9, 2017 at 7:44pm
Thank you ! Sounds promising plz keep us updated

Kind regards
Permalink Reply by Xeljanzgirl on December 31, 2016 at 2:50pm

Yes, I have all my eyelashes and eyebrows back!

Permalink Reply by kevin on January 4, 2017 at 11:32am

Hello how is your health check I am french and i wish to go in turkey i call a pharmacy the price is 430 dollars. I wish to take it long term but I am afraid of serious effects can you tell me more? Is it possible to take it for life?

Permalink Reply by Kris on January 4, 2017 at 11:45am

Yes it would be lifelong treatment, but perhaps the dose can be lowered after time. Look up Pfizer the pharmaceutical company to research the possible risks of taking Xeljanz. 

How many 5 mg tablets would you get for 430 dollars? 

Do you have AU (complete hair loss)?

Permalink Reply by kevin on January 4, 2017 at 12:49pm
Yes 56 tablet of 5mg yes i know it is a lifetime treatment i ask ci people who have pr and alopecia are ready to take it for life. Doctors think of what?
Permalink Reply by bibby on January 4, 2017 at 3:20pm

What is the cost of the 11mg tablets ? Is it possible to cut/split these tablets to save money ? 

Permalink Reply by singh on January 9, 2017 at 7:49pm
Hi Kevin yes at the moment and the evidence from people taking then stoping and losing hair suggests that it is a treatment. But if you stop you will likely lose hair. However at the moment you could say life long treatment but I feel you can use this treatment as s bridge maybe for about 36-48 months, because I feel with all the research going on now they might have a better treatment in the coming years so in theory you may not be on xeljanz treatment all your life.

Kind regards

Singh
Permalink Reply by RahulAlopecia on January 4, 2017 at 11:46am

I have been on Xeljanz for little over two weeks now and I have been taking 5mg tab twice a day. So far I see no visible hair growth. However, my hair loss have started to slow down a little bit.

Based on others experience, how long does it usually take before you can actually start seeing some results.

Thanks in advance for your time.

Permalink Reply by Alo-mom on January 4, 2017 at 12:22pm

It took about 2 months to see any noticeable growth, If your blood work is good per your doctor see if he will up it to 3 - 5 milligrams per day. Again, you have to be monitored closely.

Permalink Reply by Rascalx2 on January 5, 2017 at 1:32pm
So I have been on 15 mg of xeljanz for past month after 3 months of 10 mgs with nothing. I do have very fine peach fuzz in places on scalp. It seems to just rub out if I shower. Have a couple hairs under arms. I am AU, so i notice anything. Anybody have sxperience with peach fuzz and just rubbing out? Does it get more fuller? I have not been responding too well. This is most activity I have had since taking xeljnz.

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